TY - JOUR ID - 252441 TI - Investigating the Link Between MS and the EBV Virus JO - Personalized Medicine Journal JA - PMJ LA - en SN - 2476-5538 AU - Abbasi, Bahareh AU - Araghi, Almas AU - Akbari Aghababa, AmirHossein AD - National Institute of Genetic Engineering and Biotechnology. AD - Department of Microbiology, Faculty of Biological Sciences, North Tehran Islamic Azad University, Tehran, Iran. AD - Department of Microbiology, Faculty of Biological Science, North Branch, Islamic Azad University, Tehran, Iran Y1 - 2022 PY - 2022 VL - 7 IS - 24 SP - 23 EP - 27 KW - multiple sclerosis KW - Epstein–Barr Virus KW - MS KW - EBV KW - B-Cells KW - Infection DO - 10.22034/pmj.2022.252441 N2 - Multiple sclerosis (MS) is a disease of the central nervous system characterized by inflammation, demyelination, and neuronal damage. Epstein–Barr virus (EBV) is a human DNA herpesvirus infecting more than 90% of the world's population. EBV is the etiological agent of infectious mononucleosis (Pfeiffer's disease). Major predisposing factors for MS are certain tissue types (e.g., HLA DRB1*15:01), vitamin D deficiency, smoking, obesity, and infection with Epstein-Barr virus (EBV). This review summarizes current knowledge on the association between EBV and MS. UR - https://www.pmjournal.ir/article_252441.html L1 - https://www.pmjournal.ir/article_252441_d8b67508f0643c85eee7e10f4f61577d.pdf ER -