Role of personalized microRNA-124 Expression in Ovarian Cancer
1. Role of personalized microRNA-124 Expression in Ovarian Cancer

Babak Otoukesh; Peyman Kaghazian; Amirjouya Talaei; Bahram Boddouhi; Bahareh Heshmat

Volume 4, Issue 13 , Spring 2019, , Pages 1-5

http://dx.doi.org/10.21859/pmj04011

Abstract
  Introduction: MicroRNA-124 (miR-124) is moderated in some human malignancies and is associated with tumor advancement. But, its expression and clinical importance in ovarian carcinoma ...  Read More
EMT-TF Expression in Colorectal Cancer in Tehran Population
2. EMT-TF Expression in Colorectal Cancer in Tehran Population

Mohammad Ali Saremi; Najme Shojaee

Volume 4, Issue 14 , Summer 2019, , Pages 1-3

http://dx.doi.org/10.21859/pmj01021

Abstract
  Epithelial to mesenchymal transition (EMT) is a process by which epithelial cells lose their epithelial characteristics such as cell polarity and cell–cell contact, and gain mesenchymal ...  Read More
Evaluation of Common Mutations in Exon 2 and 3 of the K-ras Gene in Patients with Lung Cancer
3. Evaluation of Common Mutations in Exon 2 and 3 of the K-ras Gene in Patients with Lung Cancer

Mohammad Ali Saremi

Volume 4, Issue 15 , Autumn 2019, , Pages 1-3

http://dx.doi.org/10.21859/pmj01031

Abstract
  Lung cancer is the deadliest cancer in Iran after gastric cancer. The vast majority (85%) of cases of lung cancer are due to long-term tobacco smoking. About 10–15% of cases occur ...  Read More
rs78726532 TLR3 gene polymorphism with susceptibility to Hepatitis C virus infection
4. rs78726532 TLR3 gene polymorphism with susceptibility to Hepatitis C virus infection

Blnd Ibrahim Mohammed; Saeed Megdadi; Vahid Reza Esfahani

Articles in Press, Accepted Manuscript, Available Online from 10 June 2020

http://dx.doi.org/10.22034/pmj.2020.40358

Abstract
  HCV is a blood pathogen that affects approximately 180 million people worldwide. It has the ability to escape its host’s defense mechanism and is considered a resistant species. ...  Read More
Analysis of EGFR gene mutations in tissue samples of lung cancer tumors
5. Analysis of EGFR gene mutations in tissue samples of lung cancer tumors

Blnd Ibrahim Mohammed; Amir Mohammadi; Nafise Poorhasan

Volume 5, Issue 17 , Spring 2020, , Pages 1-4

http://dx.doi.org/10.22034/pmj.2020.43451

Abstract
  Lung cancer is the leading cause of cancer deaths worldwide. Approximately 25% of nonsmall-cell lung cancers have mutations in the EGFR gene, most of which occur in hotspot regions ...  Read More
Investigating the relationship between gene CYP1B1 C4326G polymorphism and the risk of cervical cancer
6. Investigating the relationship between gene CYP1B1 C4326G polymorphism and the risk of cervical cancer

Fadhil Said; Mohammad Al-Tohami; Vahidreza Esfahani

Volume 5, Issue 19 , Autumn 2020, , Pages 1-3

http://dx.doi.org/10.22034/pmj.2020.240042

Abstract
    Cervical cancer is a common and deadly cancer among women around the world. One of the genes associated with many cancers is the CYP1B1gene.Some studies have shown that polymorphisms ...  Read More
Investigation of PTEN Promoter Methylation and Its Effect on Non-Small Cell Lung Carcinoma
7. Investigation of PTEN Promoter Methylation and Its Effect on Non-Small Cell Lung Carcinoma

Maryam Hassanlou; Sohameh Mohebbi

Volume 5, Issue 20 , Winter 2021, , Pages 1-3

http://dx.doi.org/10.22034/pmj.2021.243872

Abstract
  PTEN is a tumor suppressor gene with important roles in apoptosis. This gene is located on chromosome 10q23 and is one of the most frequently inactivated genes in cancers. Severe underexpression ...  Read More
Association between rs362746 polymorphism of RELN and Schizophrenia in Iranian Patients
8. Association between rs362746 polymorphism of RELN and Schizophrenia in Iranian Patients

Shima Alimohammadi

Volume 6, Issue 21 , Spring 2021, , Pages 1-3

http://dx.doi.org/10.22034/pmj.2021.244727

Abstract
  Genetic studies, there is a potential association of RELN with some psychologicaldisorders such as Autism Spectrum Disorders (ASD) schizophrenia (SCZ). The RELNgene is located on chromosome ...  Read More
Effects of iron oxide nanoparticles on MDA-MB-231 breast breast cell line
9. Effects of iron oxide nanoparticles on MDA-MB-231 breast breast cell line

Ramadhan Ibrahim; Mohammad Ali Saremi; Mohammad Ali Keshavarz Shahbaz; Maryam forouhi

Articles in Press, Corrected Proof, Available Online from 10 June 2020

http://dx.doi.org/10.22034/pmj.2020.40359

Abstract
  Because of their small size, unique physics, and chemical properties, metal nanoparticles can easily cross obstacles and reach their target cells, which makes them an ideal choice for ...  Read More
Role of Coordinator-Donor Conformity and Personalized Case Selection in Success Rate and Quality of Family Consent
10. Role of Coordinator-Donor Conformity and Personalized Case Selection in Success Rate and Quality of Family Consent

Meysam Mojtabaee; Fariba Ghorbani; Masoud Mazaheri; Farahnaz Sadegh Beigee

Volume 4, Issue 14 , Summer 2019, , Pages 4-7

http://dx.doi.org/10.21859/pmj01022

Abstract
  Introduction: Regarding to ethnicity and racial complexity in socially heterogeneous and refugee-accepting countries, family approach for organ donation request from a deceased donor ...  Read More
Investigation of the Relationship between PDYN Gene Polymorphisms and Tendency to Heroin Use
11. Investigation of the Relationship between PDYN Gene Polymorphisms and Tendency to Heroin Use

Vahid Reza Esfahani; Mohammad Ali Saremi

Volume 4, Issue 15 , Autumn 2019, , Pages 4-6

http://dx.doi.org/10.21859/pmj01032

Abstract
  Numerous studies have been conducted to investigate the relationship between genetic factors and drug use tendency, many of which have shown a significant correlation between genetic ...  Read More
The Association between Prostate Cancer and CXCL9 Gene Expression
12. The Association between Prostate Cancer and CXCL9 Gene Expression

Ali MehdiZadeh; Fardin Khajahei; Ali Reza Miri Lavasani

Volume 5, Issue 19 , Autumn 2020, , Pages 4-6

http://dx.doi.org/10.22034/pmj.2020.240043

Abstract
  Chemokine CXCL9 is a member of the CXC family and has an important role in the chemotaxis of immune cells. In this study,  changes in the expression of gene CXCL9 in prostate cancer ...  Read More
Personalized Medicine in Bipolar Disorder
13. Personalized Medicine in Bipolar Disorder

Parham Pooladgar; Bahar Naghavi Gargari

Volume 5, Issue 20 , Winter 2021, , Pages 4-8

http://dx.doi.org/10.22034/pmj.2021.243875

Abstract
  Bipolar Disorder (BD) is a cognitive and behavioral disease with mood fluctuation  . The 6th global problem is in adults. Disease susceptibility is affected through genetic factors, ...  Read More
A relationship between two polymorphisms (rs2660 and rs1800450) and coronavirus (COVID-19) in Iranian population
14. A relationship between two polymorphisms (rs2660 and rs1800450) and coronavirus (COVID-19) in Iranian population

Zahra Sadeghi; Hossein Pakzad; Massoud Houshmand

Volume 6, Issue 21 , Spring 2021, , Pages 4-6

http://dx.doi.org/10.22034/pmj.2021.244728

Abstract
  Warning of the World Health Organization (WHO) indicates that novel coronavirus (COVID-19) is pandemic and causes global concern. COVID-19 has acute respiratory symptoms which ...  Read More
Comparison of different methods of DNA extraction from paraffin-embedded tissues
15. Comparison of different methods of DNA extraction from paraffin-embedded tissues

Ramadhan Ibrahim; Saeed Megdadi; Sareh Bakhshandeh bavarsad; Najme Shojaei

Volume 5, Issue 17 , Spring 2020, , Pages 5-8

http://dx.doi.org/10.22034/pmj.2020.43452

Abstract
  The most common human archival specimens are formalin-fixed and paraffin-embedded tissues. PCR-based techniques have been coupled with new developments in the extraction of DNA from ...  Read More
Is History of Coronary Artery Bypass Graft Surgery a Strong Determinant of Inferiority of Organ in Cadaveric Liver Donation? Emerging Role of personalized Medicine
16. Is History of Coronary Artery Bypass Graft Surgery a Strong Determinant of Inferiority of Organ in Cadaveric Liver Donation? Emerging Role of personalized Medicine

Meysam Mojtabaee; Saman Nikeghbalian; Shagin Shahryari; Siavash Gholami; Farahnaz Sadegh Beigee

Volume 4, Issue 13 , Spring 2019, , Pages 6-7

http://dx.doi.org/10.21859/pmj04012

Abstract
  Nowadays, there has been a considerable advance of personalized medicine on ascientific basis and clinical demands in cardiovascular diseases. This study investigateda history of coronary ...  Read More
Investigating the relationship between polymorphism rs406193 and the risk of prostate cancer
17. Investigating the relationship between polymorphism rs406193 and the risk of prostate cancer

Fawziah M. Mohammed; Amir Mohammadi; Najme Shojaei

Articles in Press, Corrected Proof, Available Online from 10 June 2020

http://dx.doi.org/10.22034/pmj.2020.40360

Abstract
  In many cancers, an increase in gene expression of DNMT3b has been reported. This enzyme inhibits the expression of many tumor suppressor genes through the methylation of the promoter ...  Read More
The Effect of Kombucha Tea on Oxidative Stress Parameters in Mice Treated with Silver Nanoparticles
18. The Effect of Kombucha Tea on Oxidative Stress Parameters in Mice Treated with Silver Nanoparticles

Mahsa Alikarami

Volume 4, Issue 15 , Autumn 2019, , Pages 7-9

http://dx.doi.org/10.21859/pmj01033

Abstract
  The use of silver as an antibacterial goes back to ancient times. Adding a small number of silver nanoparticles to different surfaces can cause the antimicrobial coating. Use at high ...  Read More
investigation the correlation between FGL1 expression and prognosis in gastric cancer patients
19. investigation the correlation between FGL1 expression and prognosis in gastric cancer patients

Mahnaz Saremi; Leila Moezzi

Volume 5, Issue 19 , Autumn 2020, , Pages 7-9

http://dx.doi.org/10.22034/pmj.2020.240044

Abstract
  Gastric cancer is the fourth most common cancer worldwide and it ranks second among cancer deaths. Several studies have shown that FGL2 contributes to the pathogenesis of a number of ...  Read More
Investigating the causes of antibiotic resistance in bacteria
20. Investigating the causes of antibiotic resistance in bacteria

AmirHossein Akbari Aghababa; Mona Nadi

Volume 6, Issue 21 , Spring 2021, , Pages 7-11

http://dx.doi.org/10.22034/pmj.2021.244729

Abstract
  The discovery and production of (synthetic) antibiotics in the first half of the previous century has been one of medicine’s greatest achievements. The use of antimicrobial agents ...  Read More
Personalized Medicine Journal in 2019: Reflecting on the Development of the Upcoming Role of Personalized Medicine in the Therapies
21. Personalized Medicine Journal in 2019: Reflecting on the Development of the Upcoming Role of Personalized Medicine in the Therapies

Massoud Houshmand; Seyed Hassan Saadat

Volume 4, Issue 13 , Spring 2019, , Pages 8-9

http://dx.doi.org/10.21859/pmj04013

Abstract
  In recent decades, there has been an increase in the incidence of cancer in the affected communities. However, the growth of therapeutic strategies has been very slow. Conventional ...  Read More
MTHFR Gene Expression and Promoter Methylation in Oligozoospermia Infertile Men
22. MTHFR Gene Expression and Promoter Methylation in Oligozoospermia Infertile Men

Vahid Reza Esfahani; Mohammad Ali Saremi

Volume 4, Issue 14 , Summer 2019, , Pages 8-10

http://dx.doi.org/10.21859/pmj01023

Abstract
  Methylenetetrahydrofolate reductase (MTHFR) has a critical role in spermatogenesis process and altered expression level of this gene may leads to male infertility. In the present study, ...  Read More
Evaluation of V617F JAK 2 gene mutation by high resolution Melting method in patient witherythrocytosis
23. Evaluation of V617F JAK 2 gene mutation by high resolution Melting method in patient witherythrocytosis

Fawziah M. Mohammed; Hossein Pakzad; Vahid Reza Esfahani

Volume 5, Issue 17 , Spring 2020, , Pages 9-11

http://dx.doi.org/10.22034/pmj.2020.43453

Abstract
  Although several techniques have been developed for the detection of JAK2 V617F mutation, these techniques have their disadvantages. High-resolution melting (HRM) analysis is a new, ...  Read More
Association of C677T Single Nucleotide Polymorphism of MTHFR with Susceptibility to Autism Spectrum Disorders
24. Association of C677T Single Nucleotide Polymorphism of MTHFR with Susceptibility to Autism Spectrum Disorders

Neda Mousavi-Niri; Mohammad Ali Saremi

Volume 5, Issue 20 , Winter 2021, , Pages 9-11

http://dx.doi.org/10.22034/pmj.2021.243876

Abstract
  In general, people with Autism Spectrum Disorders (ASD) have problems in social, emotional, and communication skills. Genome-Wide Association Studies (GWAS) have suggested a potential ...  Read More
Evaluation of the relationship between intronic polymorphism TPO gene and risk of type 2 diabetes in Tehran population
25. Evaluation of the relationship between intronic polymorphism TPO gene and risk of type 2 diabetes in Tehran population

Massoud Houshmand; Mehrshad Seresht-Ahmadi; Mahsa Alikarami

Articles in Press, Corrected Proof, Available Online from 10 June 2020

http://dx.doi.org/10.22034/pmj.2020.40361

Abstract
  Obesity and type 2 diabetes are two complex disorders with strong genetic backgrounds, and both disorders cause other diseases and increase mortality. FTO is a protein-coding gene located ...  Read More