Role of personalized microRNA-124 Expression in Ovarian Cancer
Role of personalized microRNA-124 Expression in Ovarian Cancer

Babak Otoukesh; Peyman Kaghazian; Amirjouya Talaei; Bahram Boddouhi; Bahareh Heshmat

Volume 4, Issue 13 , June 2019, , Pages 1-5

https://doi.org/10.21859/pmj04011

Abstract
  Introduction: MicroRNA-124 (miR-124) is moderated in some human malignancies and is associated with tumor advancement. But, its expression and clinical importance in ovarian carcinoma ...  Read More
EMT-TF Expression in Colorectal Cancer in Tehran Population
EMT-TF Expression in Colorectal Cancer in Tehran Population

Mohammad Ali Saremi; Najme Shojaee

Volume 4, Issue 14 , September 2019, , Pages 1-3

https://doi.org/10.21859/pmj01021

Abstract
  Epithelial to mesenchymal transition (EMT) is a process by which epithelial cells lose their epithelial characteristics such as cell polarity and cell–cell contact, and gain mesenchymal ...  Read More
Evaluation of Common Mutations in Exon 2 and 3 of the K-ras Gene in Patients with Lung Cancer
Evaluation of Common Mutations in Exon 2 and 3 of the K-ras Gene in Patients with Lung Cancer

Mohammad Ali Saremi

Volume 4, Issue 15 , December 2019, , Pages 1-3

https://doi.org/10.21859/pmj01031

Abstract
  Lung cancer is the deadliest cancer in Iran after gastric cancer. The vast majority (85%) of cases of lung cancer are due to long-term tobacco smoking. About 10–15% of cases occur ...  Read More
rs78726532 TLR3 gene polymorphism with susceptibility to Hepatitis C virus infection
rs78726532 TLR3 gene polymorphism with susceptibility to Hepatitis C virus infection

Blnd Ibrahim Mohammed; Saeed Megdadi; Vahid Reza Esfahani

Articles in Press, Accepted Manuscript, Available Online from 10 June 2020

https://doi.org/10.22034/pmj.2020.40358

Abstract
  HCV is a blood pathogen that affects approximately 180 million people worldwide. It has the ability to escape its host’s defense mechanism and is considered a resistant species. ...  Read More
Analysis of EGFR gene mutations in tissue samples of lung cancer tumors
Analysis of EGFR gene mutations in tissue samples of lung cancer tumors

Blnd Ibrahim Mohammed; Amir Mohammadi; Nafise Poorhasan

Volume 5, Issue 17 , June 2020, , Pages 1-4

https://doi.org/10.22034/pmj.2020.43451

Abstract
  Lung cancer is the leading cause of cancer deaths worldwide. Approximately 25% of nonsmall-cell lung cancers have mutations in the EGFR gene, most of which occur in hotspot regions ...  Read More
Investigating the relationship between gene CYP1B1 C4326G polymorphism and the risk of cervical cancer
Investigating the relationship between gene CYP1B1 C4326G polymorphism and the risk of cervical cancer

Fadhil Said; Mohammad Al-Tohami; Vahidreza Esfahani

Volume 5, Issue 19 , December 2020, , Pages 1-3

https://doi.org/10.22034/pmj.2020.240042

Abstract
    Cervical cancer is a common and deadly cancer among women around the world. One of the genes associated with many cancers is the CYP1B1gene.Some studies have shown that polymorphisms ...  Read More
Investigation of PTEN Promoter Methylation and Its Effect on Non-Small Cell Lung Carcinoma
Investigation of PTEN Promoter Methylation and Its Effect on Non-Small Cell Lung Carcinoma

Maryam Hassanlou; Sohameh Mohebbi

Volume 6, Issue 20 , March 2021, , Pages 1-3

https://doi.org/10.22034/pmj.2021.243872

Abstract
  PTEN is a tumor suppressor gene with important roles in apoptosis. This gene is located on chromosome 10q23 and is one of the most frequently inactivated genes in cancers. Severe underexpression ...  Read More
Association between rs362746 polymorphism of RELN and Schizophrenia in Iranian Patients
Association between rs362746 polymorphism of RELN and Schizophrenia in Iranian Patients

Shima Alimohammadi

Volume 6, Issue 21 , June 2021, , Pages 1-3

https://doi.org/10.22034/pmj.2021.244727

Abstract
  Genetic studies, there is a potential association of RELN with some psychologicaldisorders such as Autism Spectrum Disorders (ASD) schizophrenia (SCZ). The RELNgene is located on chromosome ...  Read More
The Effect of Immune System Aging on Cancer Progression: Review Article
The Effect of Immune System Aging on Cancer Progression: Review Article

Masoomeh Kohandani; Seyed Akbar Moosavi

Volume 6, Issue 22 , September 2021, , Pages 1-5

https://doi.org/10.22034/pmj.2021.246862

Abstract
  Cancer is largely a disease of older people; the median age for cancer diagnosis in industrialised countries is approaching 70 years of age and is expected to increase. The morbidity ...  Read More
The Role of DNA Methylation in Development and Progression of Rheumatoid Arthritis
The Role of DNA Methylation in Development and Progression of Rheumatoid Arthritis

Fawziah Mohammed; Seyed Akbar Moosavi

Volume 7, Issue 24 , 2022, , Pages 1-7

https://doi.org/10.22034/pmj.2022.252438

Abstract
  Rheumatoid arthritis (RA) is a chronic autoimmune disease of unknown etiology that results in progressive joint destruction and ultimately to disability. Currently effective biologic ...  Read More
Epigenetic as a Novel Biomarker Associated with PAH Exposure and Breast CancerRisk
Epigenetic as a Novel Biomarker Associated with PAH Exposure and Breast CancerRisk

Zainab Adel Abbas; Abbas Raheem Jebur; Abbas Ardalan; Abbas Ghasemzadeh

Volume 7, Issue 25 , June 2022, , Pages 1-14

https://doi.org/10.22034/pmj.2022.253549

Abstract
  The pathophysiology and molecular pathways of breast cancer (BC) are still unclear, but it appears that BC is caused by the interaction between genetic susceptibility and environmental ...  Read More
Effects of iron oxide nanoparticles on MDA-MB-231 breast breast cell line
Effects of iron oxide nanoparticles on MDA-MB-231 breast breast cell line

Ramadhan Ibrahim; Mohammad Ali Saremi; Mohammad Ali Keshavarz Shahbaz; Maryam forouhi

Articles in Press, Corrected Proof, Available Online from 10 June 2020

https://doi.org/10.22034/pmj.2020.40359

Abstract
  Because of their small size, unique physics, and chemical properties, metal nanoparticles can easily cross obstacles and reach their target cells, which makes them an ideal choice for ...  Read More
Role of Coordinator-Donor Conformity and Personalized Case Selection in Success Rate and Quality of Family Consent
Role of Coordinator-Donor Conformity and Personalized Case Selection in Success Rate and Quality of Family Consent

Meysam Mojtabaee; Fariba Ghorbani; Masoud Mazaheri; Farahnaz Sadegh Beigee

Volume 4, Issue 14 , September 2019, , Pages 4-7

https://doi.org/10.21859/pmj01022

Abstract
  Introduction: Regarding to ethnicity and racial complexity in socially heterogeneous and refugee-accepting countries, family approach for organ donation request from a deceased donor ...  Read More
Investigation of the Relationship between PDYN Gene Polymorphisms and Tendency to Heroin Use
Investigation of the Relationship between PDYN Gene Polymorphisms and Tendency to Heroin Use

Vahid Reza Esfahani; Mohammad Ali Saremi

Volume 4, Issue 15 , December 2019, , Pages 4-6

https://doi.org/10.21859/pmj01032

Abstract
  Numerous studies have been conducted to investigate the relationship between genetic factors and drug use tendency, many of which have shown a significant correlation between genetic ...  Read More
The Association between Prostate Cancer and CXCL9 Gene Expression
The Association between Prostate Cancer and CXCL9 Gene Expression

Ali MehdiZadeh; Fardin Khajahei; Ali Reza Miri Lavasani

Volume 5, Issue 19 , December 2020, , Pages 4-6

https://doi.org/10.22034/pmj.2020.240043

Abstract
  Chemokine CXCL9 is a member of the CXC family and has an important role in the chemotaxis of immune cells. In this study,  changes in the expression of gene CXCL9 in prostate cancer ...  Read More
Personalized Medicine in Bipolar Disorder
Personalized Medicine in Bipolar Disorder

Parham Pooladgar; Bahar Naghavi Gargari

Volume 6, Issue 20 , March 2021, , Pages 4-8

https://doi.org/10.22034/pmj.2021.243875

Abstract
  Bipolar Disorder (BD) is a cognitive and behavioral disease with mood fluctuation  . The 6th global problem is in adults. Disease susceptibility is affected through genetic factors, ...  Read More
A relationship between two polymorphisms (rs2660 and rs1800450) and coronavirus (COVID-19) in Iranian population
A relationship between two polymorphisms (rs2660 and rs1800450) and coronavirus (COVID-19) in Iranian population

Zahra Sadeghi; Hossein Pakzad; Massoud Houshmand

Volume 6, Issue 21 , June 2021, , Pages 4-6

https://doi.org/10.22034/pmj.2021.244728

Abstract
  Warning of the World Health Organization (WHO) indicates that novel coronavirus (COVID-19) is pandemic and causes global concern. COVID-19 has acute respiratory symptoms which ...  Read More
Comparison of different methods of DNA extraction from paraffin-embedded tissues
Comparison of different methods of DNA extraction from paraffin-embedded tissues

Ramadhan Ibrahim; Saeed Megdadi; Sareh Bakhshandeh bavarsad; Najme Shojaei

Volume 5, Issue 17 , June 2020, , Pages 5-8

https://doi.org/10.22034/pmj.2020.43452

Abstract
  The most common human archival specimens are formalin-fixed and paraffin-embedded tissues. PCR-based techniques have been coupled with new developments in the extraction of DNA from ...  Read More
Is History of Coronary Artery Bypass Graft Surgery a Strong Determinant of Inferiority of Organ in Cadaveric Liver Donation? Emerging Role of personalized Medicine
Is History of Coronary Artery Bypass Graft Surgery a Strong Determinant of Inferiority of Organ in Cadaveric Liver Donation? Emerging Role of personalized Medicine

Meysam Mojtabaee; Saman Nikeghbalian; Shagin Shahryari; Siavash Gholami; Farahnaz Sadegh Beigee

Volume 4, Issue 13 , June 2019, , Pages 6-7

https://doi.org/10.21859/pmj04012

Abstract
  Nowadays, there has been a considerable advance of personalized medicine on ascientific basis and clinical demands in cardiovascular diseases. This study investigateda history of coronary ...  Read More
Relationship Between FGFR4 Gene rs351855 G/A Polymorphism and the Risk of Lung Cancer in the Northern Provinces
Relationship Between FGFR4 Gene rs351855 G/A Polymorphism and the Risk of Lung Cancer in the Northern Provinces

Niyousha Dehruyeh

Volume 6, Issue 22 , September 2021, , Pages 6-9

https://doi.org/10.22034/pmj.2021.246863

Abstract
  Lung cancer is the leading cause of cancer death in men and the second leading cause of cancer death in women worldwide. FGFR is involved in a variety of cellular processes including ...  Read More
Epithelial-Mesenchymal Rransition and its Role in Breast Cancer Metastasis
Epithelial-Mesenchymal Rransition and its Role in Breast Cancer Metastasis

Avan Saeed Mohammed; Ghazal Ghajari

Volume 7, Issue 24 , 2022, , Pages 8-13

https://doi.org/10.22034/pmj.2022.252439

Abstract
  Breast cancer is the most common cancer in women and distant site metastasis is the main cause of death in breast cancer patients. Epithelial-mesenchymal transition (EMT) is defined ...  Read More
Molecular Detection of Fungal APR1 Gene in Serum of Multiple Sclerosis Patients: A Personalized Medicine Research
Molecular Detection of Fungal APR1 Gene in Serum of Multiple Sclerosis Patients: A Personalized Medicine Research

Tohid Piri-Gharaghie; Amineh Zarinnezhad; Bahar Naghian; Romina Babaei

Volume 7, Issue 25 , June 2022, , Pages 15-24

https://doi.org/10.22034/pmj.2022.253551

Abstract
  Due to the lack of reliable biomarkers and a thorough understanding of the etiology of multiple sclerosis (MS), the treatment strategy in MS requires a personalized medicine framework ...  Read More
Investigating the relationship between polymorphism rs406193 and the risk of prostate cancer
Investigating the relationship between polymorphism rs406193 and the risk of prostate cancer

Fawziah M. Mohammed; Amir Mohammadi; Najme Shojaei

Articles in Press, Corrected Proof, Available Online from 10 June 2020

https://doi.org/10.22034/pmj.2020.40360

Abstract
  In many cancers, an increase in gene expression of DNMT3b has been reported. This enzyme inhibits the expression of many tumor suppressor genes through the methylation of the promoter ...  Read More
The Effect of Kombucha Tea on Oxidative Stress Parameters in Mice Treated with Silver Nanoparticles
The Effect of Kombucha Tea on Oxidative Stress Parameters in Mice Treated with Silver Nanoparticles

Mahsa Alikarami

Volume 4, Issue 15 , December 2019, , Pages 7-9

https://doi.org/10.21859/pmj01033

Abstract
  The use of silver as an antibacterial goes back to ancient times. Adding a small number of silver nanoparticles to different surfaces can cause the antimicrobial coating. Use at high ...  Read More
investigation the correlation between FGL1 expression and prognosis in gastric cancer patients
investigation the correlation between FGL1 expression and prognosis in gastric cancer patients

Mahnaz Saremi; Leila Moezzi

Volume 5, Issue 19 , December 2020, , Pages 7-9

https://doi.org/10.22034/pmj.2020.240044

Abstract
  Gastric cancer is the fourth most common cancer worldwide and it ranks second among cancer deaths. Several studies have shown that FGL2 contributes to the pathogenesis of a number of ...  Read More