Personal Medicine Possible Treatment of Breast Cancer
Personal Medicine Possible Treatment of Breast Cancer

Fateme Davodabadi

Volume 6, Issue 23 , December 2021, , Pages 10-16

https://doi.org/10.22034/pmj.2021.249036

Abstract
  Personal medicine is based on purposeful treatment that, unlike traditional therapies, considers a person's genetic structure and medical history before establishing a treatment regimen. ...  Read More
Investigation of p16 gene promoter methylation in people with cervical cancer and women with papilloma virus infection
Investigation of p16 gene promoter methylation in people with cervical cancer and women with papilloma virus infection

Abdulkarim Karim; Hadi Yari; Ehsan Razeghian; Ali Reza Miri Lavasani

Volume 5, Issue 16 , March 2020, , Pages 12-14

https://doi.org/10.22034/pmj.2020.40428

Abstract
  Cervical cancer is the second most common cancer and an important cause of death in women worldwide. Objective biomarkers are needed to improve specificity for cervical cancer screening. ...  Read More
Pharmacogenomics for Infectious Diseases
Pharmacogenomics for Infectious Diseases

Osheen Ansari; Imran Hussain; Tabrez Jafar; Farzana Mahdi; Israr Ahmad

Volume 7, Issue 26 , September 2022, , Pages 13-23

https://doi.org/10.22034/pmj.2022.696973

Abstract
  Pharmacogenomics is the application of genetic and other omics data to specific medication selection and application for avoiding adverse drug reactions (ADR) and increasing drug potency. ...  Read More
Relationship between LncRNAs and Multiple Sclerosis (MS)
Relationship between LncRNAs and Multiple Sclerosis (MS)

Reyhaneh Tahouri; Ghasem Ghorbani Valezaghard

Volume 8, Issue 28 , March 2023, , Pages 13-19

https://doi.org/10.22034/pmj.2023.702081

Abstract
  Multiple sclerosis (MS), the most common inflammatory demyelinating illness of the central nervous system (CNS), presents a range of clinical symptoms. The body’s immune system ...  Read More
ARSA gene mutation analysis in 5 patients with metachromatic leukodystrophy
ARSA gene mutation analysis in 5 patients with metachromatic leukodystrophy

Sahar Hassannejad; Seyed Reza Hayatgheibi; Massoud Houshmand; Roya Amirinezhad

Volume 5, Issue 18 , September 2020, , Pages 14-16

https://doi.org/10.22034/pmj.2020.46381

Abstract
  Metachromatic leukodystrophyis a kind of lysosomal storage disorder caused by a deficiency in the ARSA enzyme, which is involved in the metabolism of membrane sulfatides into galactosylceramide. ...  Read More
SARS-CoV2: A Perspective on Genetic and Protein Structure, Function and Potent Treatments with a Comparison with Other Coronaviruses
SARS-CoV2: A Perspective on Genetic and Protein Structure, Function and Potent Treatments with a Comparison with Other Coronaviruses

Saghar Yousefnia

Volume 7, Issue 27 , December 2022, , Pages 14-20

https://doi.org/10.22034/pmj.2022.700888

Abstract
  Severe acute respiratory syndrome (SARS) coronavirus 2 (SARS-CoV2) leading to COVID-19 has initiated a catastrophe for humans since December 2019. Genetic and protein similarities between ...  Read More
Exploring the Attitudes, Beliefs and Perceptions of Undergraduate and Graduate Students in Bangladesh towards Precision Medicine and Pharmacogenomics Practice: A Qualitative Study
Exploring the Attitudes, Beliefs and Perceptions of Undergraduate and Graduate Students in Bangladesh towards Precision Medicine and Pharmacogenomics Practice: A Qualitative Study

Nashrifa Israt Khanom; Saima Nur; Sheikh Sabrina Mustari; Omme Jamila; Abu Sa A Dat; Md Mehade Hasan; Mushfiquzzaman Mahim; Farhana Faiza Bristy; Nasrin Tamanna; Md.Moshrraf Hossen; Swapan Kumar Das; Tanvir Ahmed; Md. Ashrafuzzaman Sapon; Md. Shafiqul Islam; Md. Monirul Islam

Volume 8, Issue 29 , June 2023, , Pages 14-24

https://doi.org/10.22034/pmj.2023.705459

Abstract
  The aim of this study is to investigate the attitude, beliefs, and perceptions among undergraduate and graduate students toward precession medicine (PM) and pharmacogenomics (PGx) practice. ...  Read More
Evaluation of miRNA-21 expression in plasma samples of breast cancer patients
Evaluation of miRNA-21 expression in plasma samples of breast cancer patients

kazhaleh Mohammadi; Mehrdad Tavakoli; Nafise Poorhasan; Maryam forouhi

Volume 5, Issue 16 , March 2020, , Pages 15-16

https://doi.org/10.22034/pmj.2020.40429

Abstract
  According to the World Health Organization, one in eight to ten women will develop breast cancer. Therefore, the development of new blood / serum markers is important as an alternative ...  Read More
SIRT1 rs7895833 and SOD1-50bp ins/del Gene vVariations in Age-Related Cataract Patients: A Case-Control Study
SIRT1 rs7895833 and SOD1-50bp ins/del Gene vVariations in Age-Related Cataract Patients: A Case-Control Study

Leila Kohan; Sahar Sharghi; Afshin Karimi

Volume 9, Issue 32 , March 2024, , Pages 16-22

https://doi.org/10.22034/pmj.2024.2024055.1029

Abstract
  Aim: Oxidative stress is one of the main factors has been implicated in pathophysiology of cataracts. Superoxide dismutase (SOD) can prepare the first line of defense versus detrimental ...  Read More
The effect of vitamin D treatment on the sperm parameters of mice treated with busulfan
The effect of vitamin D treatment on the sperm parameters of mice treated with busulfan

Sahar Hassannejad; Reza Ghamari; Mohammad Ali Saremi; Sadegh Shojaei Baghini

Volume 5, Issue 16 , March 2020, , Pages 17-19

https://doi.org/10.22034/pmj.2020.40430

Abstract
  Spermatogenesis is a very complex process that can be affected by a number of factors which may lead to reduced fertility or infertility. Busulfan kills spermatogonia stem cells and ...  Read More
Effect of ascorbic acid treatment with angiogenesis
Effect of ascorbic acid treatment with angiogenesis

Sareh Bakhshandeh Bavarsad; Amir Mohammadi; Najme Shojaei

Volume 5, Issue 18 , September 2020, , Pages 17-19

https://doi.org/10.22034/pmj.2020.46382

Abstract
  Vitamin C plays is a cofactor for enzymes involved in many processes and has effects that are important for cancer transformation, such as antioxidant defense, transcription, and epigenetic ...  Read More
Induction of Bax and Caspase-3 Genes Expression by Simultaneous Administration of Phycocyanin and Citrullus Colocynthis Extract in Human Colorectal Cell Line (HT-29)
Induction of Bax and Caspase-3 Genes Expression by Simultaneous Administration of Phycocyanin and Citrullus Colocynthis Extract in Human Colorectal Cell Line (HT-29)

Fatemeh Darabi; Halimeh Hassanpour; Parvaneh Maghami; Sohameh Mohebbi; Somayeh Arabzadeh

Volume 6, Issue 23 , December 2021, , Pages 17-24

https://doi.org/10.22034/pmj.2021.249038

Abstract
  Introduction: In this study the effect of C. colocynthis extract and phycocyanin on the growth of colon cancer cells, and the expression of Caspase 3 and Bax were investigated.Materials ...  Read More
Introduction of two candidate microRNAs, –miR-21 and miR-146a, as biomarkers in MS
Introduction of two candidate microRNAs, –miR-21 and miR-146a, as biomarkers in MS

Farzaneh Rahvar; Fawziah M. Mohammed; Mehrshad Seresht-Ahmadi; Nafise Poorhasan

Volume 5, Issue 18 , September 2020, , Pages 20-23

https://doi.org/10.22034/pmj.2020.46383

Abstract
  The roles of miRNAs in autoimmunity are only beginning to be explored; they may be involved in regulating immune responses against self-tissues.miRNAs may contribute to disease progression ...  Read More
Vitamin D Binding Protein Gene Polymorphisms and its Association with Type 2 Diabetes Mellitus in an Iranian Population
Vitamin D Binding Protein Gene Polymorphisms and its Association with Type 2 Diabetes Mellitus in an Iranian Population

Heidar Aziznejad; Ares Alizadeh; Marva Aziznejad; Zahra Sanjideh; Parisa Maziri

Volume 8, Issue 28 , March 2023, , Pages 20-25

https://doi.org/10.22034/pmj.2023.702082

Abstract
  Polymorphisms of Vitamin D-binding protein (DBP) may represent a risk factor for susceptibility to Type 2 Diabetes Mellitus (T2DM). Two polymorphisms are common at codons 420 (ACG to ...  Read More
The Emerging Role of Personalized Medicine in Immunotherapy for Ovarian Cancer
The Emerging Role of Personalized Medicine in Immunotherapy for Ovarian Cancer

Muhmmad Noor Kazkaz

Volume 7, Issue 27 , December 2022, , Pages 21-26

https://doi.org/10.22034/pmj.2022.700904

Abstract
  The ability of immunotherapy to treat ovarian cancer is currently limited, however evaluating sensitive/resistant target treatment subpopulations based on stratification by tumor biomarkers ...  Read More
Innovative Functions of Metabolomics in Individualized Health Care: A Review Study in the Field of Metabolomics
Innovative Functions of Metabolomics in Individualized Health Care: A Review Study in the Field of Metabolomics

Sara Saremi Nouri; Mehrsa Emami; Hamidreza Kabiri; Negin Rajaei

Volume 9, Issue 32 , March 2024, , Pages 23-28

https://doi.org/10.22034/pmj.2024.2024193.1033

Abstract
  Variability in medication reactions and illness susceptibility among individuals is often seen in clinical settings. Personalized medicine is now highly esteemed for its focus on prescribing ...  Read More
Personalized Medicine-based Microbiology Management of Infectious Diseases
Personalized Medicine-based Microbiology Management of Infectious Diseases

Nasim Fattahi; Neda Banaei; Naz Tavakoli Lahijani; Ali Rashmanlou; Mahnaz Saremi

Volume 7, Issue 26 , September 2022, , Pages 24-29

https://doi.org/10.22034/pmj.2022.696998

Abstract
  The current study identified pathogenic variables associated with increased mortality risk in infectious diseases using predictive analysis and a combination of genotypic, phenotypic, ...  Read More
Polycystic ovary syndrome and genetic factors influencing its development: A review article
Polycystic ovary syndrome and genetic factors influencing its development: A review article

Tohid Piri-Gharaghie

Volume 6, Issue 23 , December 2021, , Pages 25-29

https://doi.org/10.22034/pmj.2021.249631

Abstract
  Polycystic ovary syndrome (PCOS) is a common infertility disorder, affecting a significant proportion of the global population. This syndrome has been one of the most controversial ...  Read More
Personalized Medicine for Antibiotics: Pharmacological Displacement of Thiocolchicosidum as Antimicrobial Agent
Personalized Medicine for Antibiotics: Pharmacological Displacement of Thiocolchicosidum as Antimicrobial Agent

Farhad Jafari-Berenjestanaki; Faeze Hasani

Volume 8, Issue 29 , June 2023, , Pages 25-30

https://doi.org/10.22034/pmj.2023.705460

Abstract
  Due to the increasing level of bacterial antibiotic resistance (AB), it is now required to modify the dosage for customized medication using therapeutic drug monitoring. The creation ...  Read More
Personalized Medicine Approach and the Application of iPSCs in Neurological Diseases
Personalized Medicine Approach and the Application of iPSCs in Neurological Diseases

Jafar Jafari

Volume 8, Issue 28 , March 2023, , Pages 26-34

https://doi.org/10.22034/pmj.2023.702083

Abstract
  A number of animal disease models have been created in the past to investigate the molecular basis of neurological diseases and identify novel treatments, but their effectiveness has ...  Read More
Treatment Insights from Long COVID Syndrome Emerging as Neuropsychiatric Exacerbations in Autism Spectrum Disorder
Treatment Insights from Long COVID Syndrome Emerging as Neuropsychiatric Exacerbations in Autism Spectrum Disorder

Neda Banaei; Mahnaz Saremi; Mona Akbari-Ahmadabadi

Volume 7, Issue 27 , December 2022, , Pages 27-33

https://doi.org/10.22034/pmj.2022.700903

Abstract
  Even if the symptoms during the acute phase are minimal, COVID-19 not only results in severe respiratory problems but also long-term consequences. Significant long-term consequences ...  Read More
Introducing PROTAC Therapy—a Novel Tailored Approach to Lung Cancer Treatment
Introducing PROTAC Therapy—a Novel Tailored Approach to Lung Cancer Treatment

Sahar Abareshi; Yeganeh Yousefi; Niusha Zeynalniya Toosi

Volume 9, Issue 32 , March 2024, , Pages 29-35

https://doi.org/10.22034/pmj.2024.712171

Abstract
  Drug resistance in cancer is a major challenge to properly treating malignancy. Therapies aimed at proteins involved in cancer development may become less effective due to acquired ...  Read More
The Impact of Nanotechnology on the Future of Personalized Medicine
The Impact of Nanotechnology on the Future of Personalized Medicine

Razieh ghasemi; Mahkameh Baghernia

Volume 6, Issue 23 , December 2021, , Pages 30-34

https://doi.org/10.22034/pmj.2021.249632

Abstract
  Personalized medicine as a revolutionary in medicine provides medical services tailored to a person's molecular characteristics. In personalized medicine, the physician with the knowledge ...  Read More
Personalized Medicine Approach in the Treatment of Alzheimer's Disease
Personalized Medicine Approach in the Treatment of Alzheimer's Disease

Homeira Zare Chavoshy; Fereshteh Barati; Razieh Ghasemi

Volume 7, Issue 26 , September 2022, , Pages 30-33

https://doi.org/10.22034/pmj.2022.697001

Abstract
  Alzheimer's disease (AD) is a neurodegenerative disease that leads to progressive and incurable cognitive and behavioral disorders. Personalized medicine, which is also called precision ...  Read More
Correlation Between Inflammatory Aortic Disease and Rheumatoid Rarthritis Based on Personalized Medicine
Correlation Between Inflammatory Aortic Disease and Rheumatoid Rarthritis Based on Personalized Medicine

Babak Farshid; Saber Kabiri-Samani

Volume 8, Issue 29 , June 2023, , Pages 31-35

https://doi.org/10.22034/pmj.2023.705461

Abstract
  The synovial joints are most affected by the systemic autoimmune inflammatory condition known as rheumatoid arthritis (RA). A unique and underappreciated link exists between rheumatoid ...  Read More