Introduction: Regarding to ethnicity and racial complexity in socially heterogeneous and refugee-accepting countries, family approach for organ donation request from a deceased donor could be unpredictable. The problem could be settled by adherence to coordinator-donor conformity rule besides principals of donor family care. Methods: In our OPU, we have recruited a considerable quantity of organ donation coordinators (mainly medical students) with different ethnicities, dialects, and personality types. In this study, we have assessed family approach success indices in two different eras (Before 2017 and after this time). These included overall family consent and refusal rates, time interval from the first interview to actual donation, the weight of different age clusters in the donor pool and etc. Results: Considerable progress was achieved in all family approach success indices. Overall family consent rate was found to be increased from 61% in the first era to 88% in the second era (P = 0.005). The mandatory time for the coordinators to obtain family consent dropped significantly. (12.2 ± 8.6 to 6.3 ± 4.8 Hr, P = 0.02). Furthermore, the weight of precious young donors (< 40 years) increased from 36% to 47% (P = 0.05) due to more success rate in more difficult young cases. Conclusions: Appropriate recruitment of organ donation coordinators warranties more successful organ donation efforts after proper training. Decision making about suitable usage of every coordinator in a specific part of the family approach stages should be done case-by-case. This strategy could be of great benefit in ethnicity and cultural variant communities.