Original Article
Investigation of PTEN Promoter Methylation and Its Effect on Non-Small Cell Lung Carcinoma
1. Investigation of PTEN Promoter Methylation and Its Effect on Non-Small Cell Lung Carcinoma

Maryam Hassanlou; Sohameh Mohebbi

Volume 5, Issue 20 , Winter 2021, Pages 1-3

http://dx.doi.org/10.22034/pmj.2021.243872

Abstract
  PTEN is a tumor suppressor gene with important roles in apoptosis. This gene is located on chromosome 10q23 and is one of the most frequently inactivated genes in cancers. Severe underexpression ...  Read More
Original Article
Personalized Medicine in Bipolar Disorder
2. Personalized Medicine in Bipolar Disorder

Parham Pooladgar; Bahar Naghavi Gargari

Volume 5, Issue 20 , Winter 2021, Pages 4-8

http://dx.doi.org/10.22034/pmj.2021.243875

Abstract
  Bipolar Disorder (BD) is a cognitive and behavioral disease with mood fluctuation  . The 6th global problem is in adults. Disease susceptibility is affected through genetic factors, ...  Read More
Original Article
Association of C677T Single Nucleotide Polymorphism of MTHFR with Susceptibility to Autism Spectrum Disorders
3. Association of C677T Single Nucleotide Polymorphism of MTHFR with Susceptibility to Autism Spectrum Disorders

Neda Mousavi-Niri; Mohammad Ali Saremi

Volume 5, Issue 20 , Winter 2021, Pages 9-11

http://dx.doi.org/10.22034/pmj.2021.243876

Abstract
  In general, people with Autism Spectrum Disorders (ASD) have problems in social, emotional, and communication skills. Genome-Wide Association Studies (GWAS) have suggested a potential ...  Read More
Original Article
TERT Promoter Polymorphisms and Risk of Cervical Cancer
4. TERT Promoter Polymorphisms and Risk of Cervical Cancer

Aida Etemadi; Maryam Hassanlou

Volume 5, Issue 20 , Winter 2021, Pages 12-14

http://dx.doi.org/10.22034/pmj.2021.243877

Abstract
  TERT It has been shown that TERT is overexpressed in 90% of human cancers, and genetic alterations in the proximal promoter of TERT are significantly associated with a variety of different ...  Read More
Original Article
Detection and Genotyping of HPV Infection Using a New Method Based on Real-Time PCR
5. Detection and Genotyping of HPV Infection Using a New Method Based on Real-Time PCR

Abbas Ardalan; Vahidreza Esfahani

Volume 5, Issue 20 , Winter 2021, Pages 15-17

http://dx.doi.org/10.22034/pmj.2021.243879

Abstract
  The causalGiven the known relationship between the HPV infection and some malignancies, it is critical to develop methods for quick detection and quantitation of certain HPV types while ...  Read More
Original Article
Expression Evaluation of Long Non-Coding RNA TLC6 in Renal Cell Carcinoma
6. Expression Evaluation of Long Non-Coding RNA TLC6 in Renal Cell Carcinoma

Hamed Naghoosi; Somaye Arabzadeh

Volume 5, Issue 20 , Winter 2021, Pages 18-20

http://dx.doi.org/10.22034/pmj.2021.243880

Abstract
  Renal Cell Carcinomas (RCC) are a wide range of heterogeneous tumors that mainly originate in renal tubular epithelial cells. These carcinomas are more common in males older than 60. ...  Read More
Original Article
Apoptosis-Inducing Effect of Hesperidin on Breast Cancer Cell Line MCF7
7. Apoptosis-Inducing Effect of Hesperidin on Breast Cancer Cell Line MCF7

Sohameh Mohebbi; Nafise Poorhasan

Volume 5, Issue 20 , Winter 2021, Pages 21-23

http://dx.doi.org/10.22034/pmj.2021.243881

Abstract
  Hesperidin is a flavanone present in citrus fruits, such as oranges and lemons. It exerts non-toxic activities in normal cells; however, it has been reported to suppress cell proliferation ...  Read More