Maternal Age-Related Chromosomal Aneuploidy in Human Day 3 Embryo Biopsy Blastomeres in Couples Undergoing IVF Cycles in Kuwait
Volume 8, Issue 29, Spring 2023, Pages 1-7
https://doi.org/10.22034/pmj.2023.705457
Abdullah A Albahar, Megdeline G Martin, Eman KH Bahar, Rana AS Sarmiti
Abstract Preimplantation genetic diagnosis is recognized as an effective approach to rule out embryos with abnormal chromosomes in hopes of increasing the chances of a successful pregnancy. The objective of this study is to evaluate the association between types of single cell (blastomere) chromosomal aneuploidy and female partner age using Next Generation Sequencing technique. This study showed that 70.80% of tested samples had abnormal chromosomal complementation, regardless of maternal age or complexity of the abnormality present.