Personalized and Precision Medicine Journal

Abstract The synovial joints are most affected by the systemic autoimmune inflammatory condition known as rheumatoid arthritis (RA). A unique and underappreciated link exists between rheumatoid vasculitis (RV), an extra-articular symptom of RA, and Inflammatory Aortic Disease (aortitis). In this article, we describe the case of a 64-year-old lady who had RA-associated aortitis and conducted a literature search on the condition. Patients with RA-associated aortitis received an average oral steroid dosage of 40.2 mg/day of prednisolone (PSL). Due to the patient's RV-related symptoms, including epidermal ulceration, a significant rheumatoid factor titer, and a modest PSL dosage significantly alleviated the clinical features, it was assumed that RV also caused our patient's aortitis. Early identification and the start of therapy are crucial since RA-associated aortitis may be lethal if left untreated.