Where Innovations Meets Personalized and Precision Medicine
Author = Niknezhad, Mohammad Amin
Number of Articles: 1
A Review of Exosomes: Isolation Methods and Applications

A Review of Exosomes: Isolation Methods and Applications

Volume 9, Issue 35, Autumn 2024, Pages 33-43

https://doi.org/10.22034/pmj.2024.718048

Mahshid javanbakht, Mohammad Amin Niknezhad, Hanieh Rezvani

Abstract Exosomes are becoming recognized as crucial facilitators of interaction between cells. They deliver biological agents to target cells, play essential roles throughout multiple biological and pathological events, and have significant potential as innovative alternative therapies for illnesses. Exosomal communication between cells appears to have a role in the development of several illnesses, involving cancer, neurodegenerative conditions, and inflammatory disorders. Exosomes are diminutive (20–150 nm) entities characterized by a unique bilipid protein architecture. They transport and switch diverse cargos across cells and serve as noninvasive indicators for multiple disorders. Exosomes are regarded as the most effective indicators for cancer detection due to their distinctive properties. This document will examine the current uses of exosomes, their origins, and diverse isolation techniques. Furthermore, the function of exosomes and their use in biomedical studies and preclinical experiments are succinctly addressed.