Where Innovations Meets Personalized and Precision Medicine
Author = Abbasi Saeidi, Maryam
Number of Articles: 2
Managing Inflammation in Cancer Therapy: Effects of Inflammation Control on Metastasis and Treatment Response

Managing Inflammation in Cancer Therapy: Effects of Inflammation Control on Metastasis and Treatment Response

Volume 10, Issue 39, Autumn 2025, Pages 43-53

https://doi.org/10.22034/ppmj.2025.2066236.1065

Maryam Abbasi Saeidi, Mina i Ekrami Noghab

Abstract Chronic inflammation is a pivotal element in the onset and advancement of cancer. It is crucial in tumor initiation, survival, metastasis, and therapeutic resistance. This study seeks to thoroughly examine the intricate relationship between inflammation and cancer, emphasizing the role of inflammatory processes in tumor formation and their influence on cancer therapy responses. We will investigate the molecular processes behind inflammation-induced cancer progression, analyze how inflammation affects metastasis, and assess its effects on the effectiveness of treatments like chemotherapy, immunotherapy, and targeted therapies. Furthermore, we will investigate prospective therapeutic approaches for addressing inflammation in cancer treatment, emphasizing the necessity for specific modulation to enhance treatment efficacy while mitigating adverse consequences such as immune suppression or heightened infection risk. The report finishes with a discussion on prospective research avenues focused on optimizing inflammation-targeting techniques to augment the efficacy of cancer therapies and better patient outcomes. Ultimately, a deeper understanding of inflammation’s dual role in cancer could pave the way for innovative, more personalized treatment strategies that improve survival and quality of life for patients.

Systematic Review: Application of Artificial Intelligence in Breast Cancer Therapy

Systematic Review: Application of Artificial Intelligence in Breast Cancer Therapy

Volume 10, Issue 36, Winter 2025, Pages 36-47

https://doi.org/10.22034/pmj.2025.2048503.1047

Maryam Abbasi Saeidi

Abstract Background and Objective: Gene therapy can be employed to treat several disorders, including cancer. Globally, women are more frequently diagnosed with breast cancer than any other cancer type, underscoring the necessity for innovative strategies. Algorithms driven by artificial intelligence can enhance the gene therapy process for breast cancer by analyzing vast data sets, identifying intricate patterns, and classifying those patterns. This project aims to perform a literature evaluation focusing on the therapeutic uses of artificial intelligence in gene therapy for breast cancer.

Materials and Methods: For the aim of this study, data was gathered by reading previously published articles and searching the PubMed database for phrases that were relevant to the question being investigated.
Findings: The AI-driven algorithm analyzes complex molecular pathways in the human body, replicates the knowledge of scientists and physicians in clinical research, and simulates biological processes related to gene regulation, thereby improving the effectiveness of gene vectors, managing gene and drug delivery parameters, and modeling cellular behavior. This method diminishes medical errors and promotes early disease identification and drug efficacy forecasting, thereby providing patients with optimal results from advanced treatments like gene therapy with minimal side effects.
Conclusion: Over the period of the past decade, a multitude of efforts have been made to deploy various gene therapy procedures for breast cancer patients, to achieve the highest possible level of efficacy while minimizing the risk of adverse consequences. As a result, artificial intelligence is considered to be a powerful tool for improving early diagnosis and efficient gene therapy for breast cancer.