New Developments in Cancer Treatment Using CAT T Cell Therapy, a Kind of Gene Therapy
New Developments in Cancer Treatment Using CAT T Cell Therapy, a Kind of Gene Therapy

Azin Sohrabi; Mahnaz Saremi

Volume 9, Issue 32 , March 2024, , Pages 1-7

https://doi.org/10.22034/pmj.2024.2024374.1034

Abstract
  Recent research has pinpointed cancer as the primary cause of death on a global scale. Various traditional medications and cytotoxic immunotherapies have been established and are now ...  Read More
Introducing PROTAC Therapy—a Novel Tailored Approach to Lung Cancer Treatment
Introducing PROTAC Therapy—a Novel Tailored Approach to Lung Cancer Treatment

Sahar Abareshi; Yeganeh Yousefi; Niusha Zeynalniya Toosi

Volume 9, Issue 32 , March 2024, , Pages 29-35

https://doi.org/10.22034/pmj.2024.712171

Abstract
  Drug resistance in cancer is a major challenge to properly treating malignancy. Therapies aimed at proteins involved in cancer development may become less effective due to acquired ...  Read More
The Connection Between Platelets and the Development of Cancer
The Connection Between Platelets and the Development of Cancer

Golnaz Zamanian; Peyman Ghoraishizadeh; Sajad Hossein Bazrafshani

Volume 8, Issue 29 , June 2023, , Pages 36-42

https://doi.org/10.22034/pmj.2023.705462

Abstract
  Platelets are tiny (2-4 m), anucleate, hematopoietic cells that are discharged into the circulation by bone marrow megakaryocytes. Platelets were formerly thought to be the main agents ...  Read More
The Effect of Immune System Aging on Cancer Progression: Review Article
The Effect of Immune System Aging on Cancer Progression: Review Article

Masoomeh Kohandani; Seyed Akbar Moosavi

Volume 6, Issue 22 , September 2021, , Pages 1-5

https://doi.org/10.22034/pmj.2021.246862

Abstract
  Cancer is largely a disease of older people; the median age for cancer diagnosis in industrialised countries is approaching 70 years of age and is expected to increase. The morbidity ...  Read More
The Tumor Microenvironment and its Role in Tumor Progression and Metastasis
The Tumor Microenvironment and its Role in Tumor Progression and Metastasis

Sepideh Gholami Fireh; Seyed Akbar Moosavi

Volume 6, Issue 22 , September 2021, , Pages 16-22

https://doi.org/10.22034/pmj.2021.246865

Abstract
  Humans are continuously exposed to a wide of carcinogenic and mutagenic stimuli, including environmental toxins, radiation and viruses as well as other infections. Tumor metastasis ...  Read More
The Role of Mitochondria in The Development and Progression of Cancer
The Role of Mitochondria in The Development and Progression of Cancer

Fateme Davodabadi; Massoud Houshmand

Volume 6, Issue 22 , September 2021, , Pages 27-33

https://doi.org/10.22034/pmj.2021.246994

Abstract
  Mitochondria are the extra-nuclear source of DNA in cells and play an important role in cell death susceptibility,  oxidative stress regulation, metabolism, and signaling in normal ...  Read More
MicroRNA 210 as a Biomarker in Breast Cancer
MicroRNA 210 as a Biomarker in Breast Cancer

Mohamad AlJarallah; Nafise Poorhasan

Volume 5, Issue 19 , December 2020, , Pages 10-12

https://doi.org/10.22034/pmj.2020.240045

Abstract
  The increasing literature exploring the role of circulating miR-210 has clarified its potential as a promising biomarker for early detection, diagnosis and prognosis. Measuring circulating ...  Read More
Effect of chemotherapy on sperm DNA fragmentation
Effect of chemotherapy on sperm DNA fragmentation

Sadegh Sadegh Shojaei Baghini; Ramadhan Ibrahim; Hosein Ahmadi; Mona Nadi

Volume 5, Issue 18 , September 2020, , Pages 1-3

https://doi.org/10.22034/pmj.2020.46377

Abstract
  Chemotherapy and radiotherapy adversely affect spermatogenesis, a consequence that is particularly relevant to young men who have yet to establish families. The harmful effects of chemotherapy ...  Read More
The effect of vitamin D treatment on the sperm parameters of mice treated with busulfan
The effect of vitamin D treatment on the sperm parameters of mice treated with busulfan

Sahar Hassannejad; Reza Ghamari; Mohammad Ali Saremi; Sadegh Shojaei Baghini

Volume 5, Issue 16 , March 2020, , Pages 17-19

https://doi.org/10.22034/pmj.2020.40430

Abstract
  Spermatogenesis is a very complex process that can be affected by a number of factors which may lead to reduced fertility or infertility. Busulfan kills spermatogonia stem cells and ...  Read More
The Role of Curcumin Supplementation on the Side Effects of Busulfan and the Process of Apoptosis
The Role of Curcumin Supplementation on the Side Effects of Busulfan and the Process of Apoptosis

Nafise Poorhasan

Volume 4, Issue 15 , December 2019, , Pages 10-12

https://doi.org/10.21859/pmj01034

Abstract
  One of the most well-known side effects of anticancer drugs is the disruption of spermatogenesis. One of the most important causes of infertility in men is impaired spermatogenesis. ...  Read More
Personalized Medicine Journal in 2019: Reflecting on the Development of the Upcoming Role of Personalized Medicine in the Therapies
Personalized Medicine Journal in 2019: Reflecting on the Development of the Upcoming Role of Personalized Medicine in the Therapies

Massoud Houshmand; Seyed Hassan Saadat

Volume 4, Issue 13 , June 2019, , Pages 8-9

https://doi.org/10.21859/pmj04013

Abstract
  In recent decades, there has been an increase in the incidence of cancer in the affected communities. However, the growth of therapeutic strategies has been very slow. Conventional ...  Read More