AmitisGen TECH Dev Group Personalized and Precision Medicine Journal 3115-7874 7 24 2022 03 20 A Review of the Role of Exosomes in Prostate Cancer 28 32 252442 10.22034/pmj.2022.252442 EN Rafid A Abdulkareem Genetic engineering and biotechnology Institute, Baghdad University, Iraq. Seyed Majid Hashemi Fard AmitisGen Lab, Food and Drug Administration of Iran Ministry of Health and Medical Education. Tehran, Iran Masoomeh Kohandani Master of Science in Cellular and Molecular Biology, Department of cell and Molecular Biology, Karazmi University, Tehran, Iran Journal Article 2021 11 03 Prostate cancer (PCa) is the most common solid tumor in men. While patients with local PCa have better prognostic survival, patients with metastatic PCa have relatively high mortality rates. Exosomes (and other extracellular vesicles) are now part of the cancer research landscape, involved both as players in pathophysiological mechanisms, as biomarkers of the cancer process, and as therapeutic tools. Exosomes contain miRNAs, mRNAs, and proteins with the potential to regulate signaling pathways in recipient cells. Accumulating evidence indicates that exosomes play important roles in cell communication and tumor progression and are suitable for monitoring PCa progression and metastasis. https://www.pmjournal.ir/article_252442_4214569dee5a9894fe01113960998e47.pdf