AmitisGen TECH Dev Group Personalized and Precision Medicine Journal 3115-7874 5 16 2020 03 01 The effect of vitamin D treatment on the sperm parameters of mice treated with busulfan 17 19 40430 10.22034/pmj.2020.40430 EN Sahar Hassannejad Researcher and lecture assistant at the Medical Laboratory Science Department, Knowledge University, Kurdistan Region, Erbil, Iraq Reza Ghamari Genome research center, National Institute of Genetics Engineering and Biotechnology, Tehran, Iran. Mohammad Ali Saremi Personalized Medicine Research Center of AmitisGen, Tehran, Iran Sadegh Shojaei Baghini Plant Biotechnology, Agriculture Biotechnology Department, National Institute of Genetics Engineering and Biotechnology, Tehran, Iran. Journal Article 2020 01 01 Spermatogenesis is a very complex process that can be affected by a number of factors which may lead to reduced fertility or infertility. Busulfan kills spermatogonia stem cells and disrupts the connections between Sertoli and spermatogonia cells at base layers. Moreover, vitamin D is very important in the reproductive system of men. In this study, the effect of vitamin D on biosulfur-induced azoospermia in mice was investigated. The results showed an increase in the quality of sperm parameters in the group treated with vitamin D. https://www.pmjournal.ir/article_40430_f999094362eeb32f2ef5a275991df98b.pdf