Personalized Medicine Journal is an open access Publication, accepting articles in Persian since 2016 until 2019. Afterwards, to share our knowledge worldwide, PMJ has started publishing English articles. PMJ welcomes original, review, novel and high-impact articles related to the personalized medicine issues. PMJ has been indexed in databases; Google scholar, Magiran, and CIVILICA

All submitted manuscripts are checked for similarity through a trustworthy software named iThenticate to be assured about its originality and then rigorously peer-reviewed by the reviewers. The review process of the manuscript normally takes 4-8 weeks. In addition, PMJ awards a prize to the most innovative article of the quarterly.

Original Article
Evaluation of LBX-2AS1 Gene Expression in Patients with Colorectal Cancer
1. Evaluation of LBX-2AS1 Gene Expression in Patients with Colorectal Cancer

Yasaman Mohammadizadeh

Volume 6, Issue 23 , December 2021, Pages 1-4

http://dx.doi.org/10.22034/pmj.2021.249034

Abstract
  Colorectal Cancer (CRC) is the third most common cancer in Iranian men and the fourth most common cancer in women. Recent studies have shown that lncRNAs may also engage in remodeling ...  Read More
Original Article
Methylenetetrahydrofolate Reductase C677T (rs1801133) Polymorphism and Pemetrexed Treatment Outcome in Patients with Non–Small-Cell Lung Cancer
2. Methylenetetrahydrofolate Reductase C677T (rs1801133) Polymorphism and Pemetrexed Treatment Outcome in Patients with Non–Small-Cell Lung Cancer

Mohammad Hadi Abbasian; Nafiseh Ansarinejad; Tayeb Ramim; Farshid Fardad; Bahareh Abbasi

Volume 6, Issue 23 , December 2021, Pages 5-9

http://dx.doi.org/10.22034/pmj.2021.249035

Abstract
  Background: Lung cancer is the first cause of cancer deaths in the world. Pemetrexed is an antifolate drug used as a first or second-line in the treatment of advanced non-small cell ...  Read More
Review Article
Personal Medicine Possible Treatment of Breast Cancer
3. Personal Medicine Possible Treatment of Breast Cancer

Fateme Davodabadi; Massoud Houshmand

Volume 6, Issue 23 , December 2021, Pages 10-16

http://dx.doi.org/10.22034/pmj.2021.249036

Abstract
  Personal medicine is based on purposeful treatment that, unlike traditional therapies, considers a person's genetic structure and medical history before establishing a treatment regimen. ...  Read More
Original Article
Induction of Bax and Caspase-3 Genes Expression by Simultaneous Administration of Phycocyanin and Citrullus Colocynthis Extract in Human Colorectal Cell Line (HT-29)
4. Induction of Bax and Caspase-3 Genes Expression by Simultaneous Administration of Phycocyanin and Citrullus Colocynthis Extract in Human Colorectal Cell Line (HT-29)

Fatemeh Darabi; Halimeh Hassanpour; Parvaneh Maghami; Sohameh Mohebbi; Somayeh Arabzadeh

Volume 6, Issue 23 , December 2021, Pages 17-24

http://dx.doi.org/10.22034/pmj.2021.249038

Abstract
  Introduction: In this study the effect of C. colocynthis extract and phycocyanin on the growth of colon cancer cells, and the expression of Caspase 3 and Bax were investigated.Materials ...  Read More
Review Article
Polycystic ovary syndrome and genetic factors influencing its development: A review article
5. Polycystic ovary syndrome and genetic factors influencing its development: A review article

Tohid Piri-Gharaghie

Volume 6, Issue 23 , December 2021, Pages 25-29

http://dx.doi.org/10.22034/pmj.2021.249631

Abstract
  Polycystic ovary syndrome (PCOS) is a common infertility disorder, affecting a significant proportion of the global population. This syndrome has been one of the most controversial ...  Read More
Review Article
The Impact of Nanotechnology on the Future of Personalized Medicine
6. The Impact of Nanotechnology on the Future of Personalized Medicine

Razieh ghasemi; Mahkameh Baghernia

Volume 6, Issue 23 , December 2021, Pages 30-34

http://dx.doi.org/10.22034/pmj.2021.249632

Abstract
  Personalized medicine as a revolutionary in medicine provides medical services tailored to a person's molecular characteristics. In personalized medicine, the physician with the knowledge ...  Read More
Comparison of different methods of DNA extraction from paraffin-embedded tissues
1. Comparison of different methods of DNA extraction from paraffin-embedded tissues

Ramadhan Ibrahim; Saeed Megdadi; Sareh Bakhshandeh bavarsad; Najme Shojaei

Volume 5, Issue 17 , June 2020, , Pages 5-8

http://dx.doi.org/10.22034/pmj.2020.43452

Abstract
  The most common human archival specimens are formalin-fixed and paraffin-embedded tissues. PCR-based techniques have been coupled with new developments in the extraction of DNA from ...  Read More
Increased expression of the lnc H19 gene in the plasma of people with breast cancer
2. Increased expression of the lnc H19 gene in the plasma of people with breast cancer

kazhaleh Mohammadi; Sadegh Shojaei Baghini; Mohammad Ali Saremi

Volume 5, Issue 17 , June 2020, , Pages 12-14

http://dx.doi.org/10.22034/pmj.2020.43454

Abstract
  The majority of ncRNAs are known as long non-coding RNAs (lncRNAs) whose length exceeds 200 nucleotides. H19, a lncRNA, is the transcription product of the H19 gene, an oncogene in ...  Read More
Analysis of EGFR gene mutations in tissue samples of lung cancer tumors
3. Analysis of EGFR gene mutations in tissue samples of lung cancer tumors

Blnd Ibrahim Mohammed; Amir Mohammadi; Nafise Poorhasan

Volume 5, Issue 17 , June 2020, , Pages 1-4

http://dx.doi.org/10.22034/pmj.2020.43451

Abstract
  Lung cancer is the leading cause of cancer deaths worldwide. Approximately 25% of nonsmall-cell lung cancers have mutations in the EGFR gene, most of which occur in hotspot regions ...  Read More
Methylenetetrahydrofolate Reductase C677T (rs1801133) Polymorphism and Pemetrexed Treatment Outcome in Patients with Non–Small-Cell Lung Cancer
4. Methylenetetrahydrofolate Reductase C677T (rs1801133) Polymorphism and Pemetrexed Treatment Outcome in Patients with Non–Small-Cell Lung Cancer

Mohammad Hadi Abbasian; Nafiseh Ansarinejad; Tayeb Ramim; Farshid Fardad; Bahareh Abbasi

Volume 6, Issue 23 , December 2021, , Pages 5-9

http://dx.doi.org/10.22034/pmj.2021.249035

Abstract
  Background: Lung cancer is the first cause of cancer deaths in the world. Pemetrexed is an antifolate drug used as a first or second-line in the treatment of advanced non-small cell ...  Read More
Effect of ascorbic acid treatment with angiogenesis
5. Effect of ascorbic acid treatment with angiogenesis

Sareh Bakhshandeh Bavarsad; Amir Mohammadi; Najme Shojaei

Volume 5, Issue 18 , September 2020, , Pages 17-19

http://dx.doi.org/10.22034/pmj.2020.46382

Abstract
  Vitamin C plays is a cofactor for enzymes involved in many processes and has effects that are important for cancer transformation, such as antioxidant defense, transcription, and epigenetic ...  Read More
Original Article
rs78726532 TLR3 gene polymorphism with susceptibility to Hepatitis C virus infection
1. rs78726532 TLR3 gene polymorphism with susceptibility to Hepatitis C virus infection

Blnd Ibrahim Mohammed; Saeed Megdadi; Vahid Reza Esfahani

Articles in Press, Accepted Manuscript, Available Online from 10 June 2020

http://dx.doi.org/10.22034/pmj.2020.40358

Abstract
  HCV is a blood pathogen that affects approximately 180 million people worldwide. It has the ability to escape its host’s defense mechanism and is considered a resistant species. ...  Read More
Original Article
Effects of iron oxide nanoparticles on MDA-MB-231 breast breast cell line
2. Effects of iron oxide nanoparticles on MDA-MB-231 breast breast cell line

Ramadhan Ibrahim; Mohammad Ali Saremi; Mohammad Ali Keshavarz Shahbaz; Maryam forouhi

Articles in Press, Corrected Proof, Available Online from 10 June 2020

http://dx.doi.org/10.22034/pmj.2020.40359

Abstract
  Because of their small size, unique physics, and chemical properties, metal nanoparticles can easily cross obstacles and reach their target cells, which makes them an ideal choice for ...  Read More
Original Article
Investigating the relationship between polymorphism rs406193 and the risk of prostate cancer
3. Investigating the relationship between polymorphism rs406193 and the risk of prostate cancer

Fawziah M. Mohammed; Amir Mohammadi; Najme Shojaei

Articles in Press, Corrected Proof, Available Online from 10 June 2020

http://dx.doi.org/10.22034/pmj.2020.40360

Abstract
  In many cancers, an increase in gene expression of DNMT3b has been reported. This enzyme inhibits the expression of many tumor suppressor genes through the methylation of the promoter ...  Read More
Evaluation of the relationship between intronic polymorphism TPO gene and risk of type 2 diabetes in Tehran population
4. Evaluation of the relationship between intronic polymorphism TPO gene and risk of type 2 diabetes in Tehran population

Massoud Houshmand; Mehrshad Seresht-Ahmadi; Mahsa Alikarami

Articles in Press, Corrected Proof, Available Online from 10 June 2020

http://dx.doi.org/10.22034/pmj.2020.40361

Abstract
  Obesity and type 2 diabetes are two complex disorders with strong genetic backgrounds, and both disorders cause other diseases and increase mortality. FTO is a protein-coding gene located ...  Read More
Original Article
Investigation of p16 gene promoter methylation in people with cervical cancer and women with papilloma virus infection
5. Investigation of p16 gene promoter methylation in people with cervical cancer and women with papilloma virus infection

Abdulkarim Karim; Hadi Yari; Ehsan Razeghian; Ali Reza Miri Lavasani

Articles in Press, Corrected Proof, Available Online from 10 June 2020

http://dx.doi.org/10.22034/pmj.2020.40362

Abstract
  Cervical cancer is the second most common cancer and an important cause of death in women worldwide. Objective biomarkers are needed to improve specificity for cervical cancer screening. ...  Read More
Evaluation of miRNA-21 expression in plasma samples of breast cancer patients
6. Evaluation of miRNA-21 expression in plasma samples of breast cancer patients

kazhaleh Mohammadi; Mehrdad Tavakoli; Nafise Poorhasan; Maryam forouhi

Articles in Press, Corrected Proof, Available Online from 10 June 2020

http://dx.doi.org/10.22034/pmj.2020.40363

Abstract
  According to the World Health Organization, one in eight to ten women will develop breast cancer. Therefore, the development of new blood / serum markers is important as an alternative ...  Read More
Original Article
The effect of vitamin D treatment on the sperm parameters of mice treated with busulfan
7. The effect of vitamin D treatment on the sperm parameters of mice treated with busulfan

Sahar Hassannejad; Reza Ghamari; Mohammad Ali Saremi; Sadegh Shojaei Baghini

Articles in Press, Corrected Proof, Available Online from 10 June 2020

http://dx.doi.org/10.22034/pmj.2020.40364

Abstract
  Spermatogenesis is a very complex process that can be affected by a number of factors which may lead to reduced fertility or infertility. Busulfan kills spermatogonia stem cells and ...  Read More

Publisher:
AmitisGen Med Tech Group

Editor-in-Chief:
  Prof. Massoud Houshmand

Senior Editor:
  Dr. Roya Amirinejad

Managing Editor:
  Dr. Mohammad Ali Saremi

Executive Manager:
  Nayyere Moslehi


Frequency: Quarterly

Online ISSN: 2717-3860

Indexing and Abstracting

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