Personalized Medicine Journal is an open access double-blind peer reviewed publication which is published by AmitisGen Med Tech Group concerned with new concepts and findings in areas related to the personalized medicine issues. PMJ is a quarterly publication, which welcomes original, review, novel and high-impact articles in jornal scope (See journal scope)All submitted manuscripts are checked for similarity through a trustworthy software named iThenticate to be assured about its originality and then rigorously peer-reviewed by the reviewers. The review process of the manuscript normally takes 4-8 weeks. In addition, PMJ awards a prize to the most innovative article of the quarterly. (Read more...)

        

Review Article
Personalized medicine Related to Gene Therapy, Ethics
Personalized medicine Related to Gene Therapy, Ethics

Parham Pooladgar

Volume 7, Issue 26 , September 2022, Pages 1-5

https://doi.org/10.22034/pmj.2022.696893

Abstract
  Gene therapy, as an experimental therapy, is applied for the treatment of diseases through modification of genes. Gene therapy corrects the mutated genes. Somatic and germline gene ...  Read More
Original Article
The Protective Effect of Ganoderma Lucidum in Mice-Exposed to Sertraline
The Protective Effect of Ganoderma Lucidum in Mice-Exposed to Sertraline

Ghazal Ghajari; Arijit Chakraborty; Seyed Akbar Moosavi; Mahnaz Saremi

Volume 7, Issue 26 , September 2022, Pages 6-12

https://doi.org/10.22034/pmj.2022.696904

Abstract
  The goal of precision medicine (PM) is to provide each patient with the treatment and therapy with the optimum  results without significant adverse side effects. PM play an  essential ...  Read More
Review Article
Pharmacogenomics for Infectious Diseases
Pharmacogenomics for Infectious Diseases

Osheen Ansari; Imran Hussain; Tabrez Jafar; Farzana Mahdi; Israr Ahmad

Volume 7, Issue 26 , September 2022, Pages 13-23

https://doi.org/10.22034/pmj.2022.696973

Abstract
  Pharmacogenomics is the application of genetic and other omics data to specific medication selection and application for avoiding adverse drug reactions (ADR) and increasing drug potency. ...  Read More
Review Article
Personalized Medicine-based Microbiology Management of Infectious Diseases
Personalized Medicine-based Microbiology Management of Infectious Diseases

Nasim Fattahi; Neda Banaei; Naz Tavakoli Lahijani; Ali Rashmanlou; Mahnaz Saremi

Volume 7, Issue 26 , September 2022, Pages 24-29

https://doi.org/10.22034/pmj.2022.696998

Abstract
  The current study identified pathogenic variables associated with increased mortality risk in infectious diseases using predictive analysis and a combination of genotypic, phenotypic, ...  Read More
Review Article
Personalized Medicine Approach in the Treatment of Alzheimer's Disease
Personalized Medicine Approach in the Treatment of Alzheimer's Disease

Homeira Zare Chavoshy; Fereshteh Barati; Razieh Ghasemi

Volume 7, Issue 26 , September 2022, Pages 30-32

https://doi.org/10.22034/pmj.2022.697001

Abstract
  Alzheimer's disease (AD) is a neurodegenerative disease that leads to progressive and incurable cognitive and behavioral disorders. Personalized medicine, which is also called precision ...  Read More
Comparison of different methods of DNA extraction from paraffin-embedded tissues
Comparison of different methods of DNA extraction from paraffin-embedded tissues

Ramadhan Ibrahim; Saeed Megdadi; Sareh Bakhshandeh bavarsad; Najme Shojaei

Volume 5, Issue 17 , June 2020, , Pages 5-8

https://doi.org/10.22034/pmj.2020.43452

Abstract
  The most common human archival specimens are formalin-fixed and paraffin-embedded tissues. PCR-based techniques have been coupled with new developments in the extraction of DNA from ...  Read More
Increased expression of the lnc H19 gene in the plasma of people with breast cancer
Increased expression of the lnc H19 gene in the plasma of people with breast cancer

kazhaleh Mohammadi; Sadegh Shojaei Baghini; Mohammad Ali Saremi

Volume 5, Issue 17 , June 2020, , Pages 12-14

https://doi.org/10.22034/pmj.2020.43454

Abstract
  The majority of ncRNAs are known as long non-coding RNAs (lncRNAs) whose length exceeds 200 nucleotides. H19, a lncRNA, is the transcription product of the H19 gene, an oncogene in ...  Read More
Analysis of EGFR gene mutations in tissue samples of lung cancer tumors
Analysis of EGFR gene mutations in tissue samples of lung cancer tumors

Blnd Ibrahim Mohammed; Amir Mohammadi; Nafise Poorhasan

Volume 5, Issue 17 , June 2020, , Pages 1-4

https://doi.org/10.22034/pmj.2020.43451

Abstract
  Lung cancer is the leading cause of cancer deaths worldwide. Approximately 25% of nonsmall-cell lung cancers have mutations in the EGFR gene, most of which occur in hotspot regions ...  Read More
Methylenetetrahydrofolate Reductase C677T (rs1801133) Polymorphism and Pemetrexed Treatment Outcome in Patients with Non–Small-Cell Lung Cancer
Methylenetetrahydrofolate Reductase C677T (rs1801133) Polymorphism and Pemetrexed Treatment Outcome in Patients with Non–Small-Cell Lung Cancer

Mohammad Hadi Abbasian; Nafiseh Ansarinejad; Tayeb Ramim; Farshid Fardad; Bahareh Abbasi

Volume 6, Issue 23 , December 2021, , Pages 5-9

https://doi.org/10.22034/pmj.2021.249035

Abstract
  Background: Lung cancer is the first cause of cancer deaths in the world. Pemetrexed is an antifolate drug used as a first or second-line in the treatment of advanced non-small cell ...  Read More
Effect of ascorbic acid treatment with angiogenesis
Effect of ascorbic acid treatment with angiogenesis

Sareh Bakhshandeh Bavarsad; Amir Mohammadi; Najme Shojaei

Volume 5, Issue 18 , September 2020, , Pages 17-19

https://doi.org/10.22034/pmj.2020.46382

Abstract
  Vitamin C plays is a cofactor for enzymes involved in many processes and has effects that are important for cancer transformation, such as antioxidant defense, transcription, and epigenetic ...  Read More
Original Article
rs78726532 TLR3 gene polymorphism with susceptibility to Hepatitis C virus infection
rs78726532 TLR3 gene polymorphism with susceptibility to Hepatitis C virus infection

Blnd Ibrahim Mohammed; Saeed Megdadi; Vahid Reza Esfahani

Articles in Press, Accepted Manuscript, Available Online from 10 June 2020

https://doi.org/10.22034/pmj.2020.40358

Abstract
  HCV is a blood pathogen that affects approximately 180 million people worldwide. It has the ability to escape its host’s defense mechanism and is considered a resistant species. ...  Read More
Original Article
Effects of iron oxide nanoparticles on MDA-MB-231 breast breast cell line
Effects of iron oxide nanoparticles on MDA-MB-231 breast breast cell line

Ramadhan Ibrahim; Mohammad Ali Saremi; Mohammad Ali Keshavarz Shahbaz; Maryam forouhi

Articles in Press, Corrected Proof, Available Online from 10 June 2020

https://doi.org/10.22034/pmj.2020.40359

Abstract
  Because of their small size, unique physics, and chemical properties, metal nanoparticles can easily cross obstacles and reach their target cells, which makes them an ideal choice for ...  Read More
Original Article
Investigating the relationship between polymorphism rs406193 and the risk of prostate cancer
Investigating the relationship between polymorphism rs406193 and the risk of prostate cancer

Fawziah M. Mohammed; Amir Mohammadi; Najme Shojaei

Articles in Press, Corrected Proof, Available Online from 10 June 2020

https://doi.org/10.22034/pmj.2020.40360

Abstract
  In many cancers, an increase in gene expression of DNMT3b has been reported. This enzyme inhibits the expression of many tumor suppressor genes through the methylation of the promoter ...  Read More
Evaluation of the relationship between intronic polymorphism TPO gene and risk of type 2 diabetes in Tehran population
Evaluation of the relationship between intronic polymorphism TPO gene and risk of type 2 diabetes in Tehran population

Massoud Houshmand; Mehrshad Seresht-Ahmadi; Mahsa Alikarami

Articles in Press, Corrected Proof, Available Online from 10 June 2020

https://doi.org/10.22034/pmj.2020.40361

Abstract
  Obesity and type 2 diabetes are two complex disorders with strong genetic backgrounds, and both disorders cause other diseases and increase mortality. FTO is a protein-coding gene located ...  Read More
Original Article
Investigation of p16 gene promoter methylation in people with cervical cancer and women with papilloma virus infection
Investigation of p16 gene promoter methylation in people with cervical cancer and women with papilloma virus infection

Abdulkarim Karim; Hadi Yari; Ehsan Razeghian; Ali Reza Miri Lavasani

Articles in Press, Corrected Proof, Available Online from 10 June 2020

https://doi.org/10.22034/pmj.2020.40362

Abstract
  Cervical cancer is the second most common cancer and an important cause of death in women worldwide. Objective biomarkers are needed to improve specificity for cervical cancer screening. ...  Read More
Evaluation of miRNA-21 expression in plasma samples of breast cancer patients
Evaluation of miRNA-21 expression in plasma samples of breast cancer patients

kazhaleh Mohammadi; Mehrdad Tavakoli; Nafise Poorhasan; Maryam forouhi

Articles in Press, Corrected Proof, Available Online from 10 June 2020

https://doi.org/10.22034/pmj.2020.40363

Abstract
  According to the World Health Organization, one in eight to ten women will develop breast cancer. Therefore, the development of new blood / serum markers is important as an alternative ...  Read More
Original Article
The effect of vitamin D treatment on the sperm parameters of mice treated with busulfan
The effect of vitamin D treatment on the sperm parameters of mice treated with busulfan

Sahar Hassannejad; Reza Ghamari; Mohammad Ali Saremi; Sadegh Shojaei Baghini

Articles in Press, Corrected Proof, Available Online from 10 June 2020

https://doi.org/10.22034/pmj.2020.40364

Abstract
  Spermatogenesis is a very complex process that can be affected by a number of factors which may lead to reduced fertility or infertility. Busulfan kills spermatogonia stem cells and ...  Read More

Publisher:
AmitisGen Med Tech Group

Editor-in-Chief:
Prof. Massoud Houshmand

Senior Editor:
Dr.Roya Amirinejad

Editorial Manager:
Dr. Mohammad Ali Saremi

Executive Manager:
Nayyere Moslehi


Frequency: Quarterly

Online ISSN: 2717-3860

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