Personalized Medicine Journal is an open access double-blind peer reviewed publication which is published by AmitisGen TECH Dev Group concerned with new concepts and findings in areas related to the personalized medicine issues. PMJ is a quarterly publication, which welcomes original, review, novel and high-impact articles in jornal scope (See journal scope)All submitted manuscripts are checked for similarity through a trustworthy software named iThenticate to be assured about its originality and then rigorously peer-reviewed by the reviewers. The review process of the manuscript normally takes 4-8 weeks. In addition, PMJ awards a prize to the most innovative article of the quarterly. (Read more...)

        

Review Article
Your Body on a Chip: Functional Testing for Personalized Medicine
Your Body on a Chip: Functional Testing for Personalized Medicine

Mona Aghassizadeh-Sherbaf; Jumi Bora; Aynaz Mazandarani

Volume 7, Issue 27 , December 2022, Pages 1-7

https://doi.org/10.22034/pmj.2022.700885

Abstract
  Despite the well-known high prevalence of failure in drug development, recent advancements in tissue engineering and microfabrication have helped to create microphysiological systems ...  Read More
Original Article
Histomorphometric Study Based on Personal Medicine Effect of Propiconazole on Bone Growth Plate of Male Gerbil
Histomorphometric Study Based on Personal Medicine Effect of Propiconazole on Bone Growth Plate of Male Gerbil

Saber Kabiri-Samani; Hamidreza Kabiri

Volume 7, Issue 27 , December 2022, Pages 8-13

https://doi.org/10.22034/pmj.2022.700887

Abstract
  Propiconazole is a systemic fungicide from the triazole group used to control a wide range of diseases. This poison causes cellular, genetic and metabolic damage in animals. A bone ...  Read More
Review Article
SARS-CoV2: A Perspective on Genetic and Protein Structure, Function and Potent Treatments with a Comparison with Other Coronaviruses
SARS-CoV2: A Perspective on Genetic and Protein Structure, Function and Potent Treatments with a Comparison with Other Coronaviruses

Saghar Yousefnia

Volume 7, Issue 27 , December 2022, Pages 14-20

https://doi.org/10.22034/pmj.2022.700888

Abstract
  Severe acute respiratory syndrome (SARS) coronavirus 2 (SARS-CoV2) leading to COVID-19 has initiated a catastrophe for humans since December 2019. Genetic and protein similarities between ...  Read More
Review Article
The Emerging Role of Personalized Medicine in Immunotherapy for Ovarian Cancer
The Emerging Role of Personalized Medicine in Immunotherapy for Ovarian Cancer

Muhmmad Noor Kazkaz

Volume 7, Issue 27 , December 2022, Pages 21-26

https://doi.org/10.22034/pmj.2022.700904

Abstract
  The ability of immunotherapy to treat ovarian cancer is currently limited, however evaluating sensitive/resistant target treatment subpopulations based on stratification by tumor biomarkers ...  Read More
Original Article
Treatment Insights from Long COVID Syndrome Emerging as Neuropsychiatric Exacerbations in Autism Spectrum Disorder
Treatment Insights from Long COVID Syndrome Emerging as Neuropsychiatric Exacerbations in Autism Spectrum Disorder

Neda Banaei; Mahnaz Saremi; Mona Akbari-Ahmadabadi

Volume 7, Issue 27 , December 2022, Pages 27-33

https://doi.org/10.22034/pmj.2022.700903

Abstract
  Even if the symptoms during the acute phase are minimal, COVID-19 not only results in severe respiratory problems but also long-term consequences. Significant long-term consequences ...  Read More
Review Article
Opportunities and Challenges in Using Cancer Organoids Derived from Patients in Personalized Medicine
Opportunities and Challenges in Using Cancer Organoids Derived from Patients in Personalized Medicine

Shorouk Fathi Ahmed

Volume 7, Issue 27 , December 2022, Pages 34-41

https://doi.org/10.22034/pmj.2022.700902

Abstract
  A model system for precision medicine has been suggested using tumor organoids. Tumor organoids are unique for cancer research on a patient-by-patient basis because they are able to ...  Read More
Comparison of different methods of DNA extraction from paraffin-embedded tissues
Comparison of different methods of DNA extraction from paraffin-embedded tissues

Ramadhan Ibrahim; Saeed Megdadi; Sareh Bakhshandeh bavarsad; Najme Shojaei

Volume 5, Issue 17 , June 2020, , Pages 5-8

https://doi.org/10.22034/pmj.2020.43452

Abstract
  The most common human archival specimens are formalin-fixed and paraffin-embedded tissues. PCR-based techniques have been coupled with new developments in the extraction of DNA from ...  Read More
Increased expression of the lnc H19 gene in the plasma of people with breast cancer
Increased expression of the lnc H19 gene in the plasma of people with breast cancer

kazhaleh Mohammadi; Sadegh Shojaei Baghini; Mohammad Ali Saremi

Volume 5, Issue 17 , June 2020, , Pages 12-14

https://doi.org/10.22034/pmj.2020.43454

Abstract
  The majority of ncRNAs are known as long non-coding RNAs (lncRNAs) whose length exceeds 200 nucleotides. H19, a lncRNA, is the transcription product of the H19 gene, an oncogene in ...  Read More
Analysis of EGFR gene mutations in tissue samples of lung cancer tumors
Analysis of EGFR gene mutations in tissue samples of lung cancer tumors

Blnd Ibrahim Mohammed; Amir Mohammadi; Nafise Poorhasan

Volume 5, Issue 17 , June 2020, , Pages 1-4

https://doi.org/10.22034/pmj.2020.43451

Abstract
  Lung cancer is the leading cause of cancer deaths worldwide. Approximately 25% of nonsmall-cell lung cancers have mutations in the EGFR gene, most of which occur in hotspot regions ...  Read More
Methylenetetrahydrofolate Reductase C677T (rs1801133) Polymorphism and Pemetrexed Treatment Outcome in Patients with Non–Small-Cell Lung Cancer
Methylenetetrahydrofolate Reductase C677T (rs1801133) Polymorphism and Pemetrexed Treatment Outcome in Patients with Non–Small-Cell Lung Cancer

Mohammad Hadi Abbasian; Nafiseh Ansarinejad; Tayeb Ramim; Farshid Fardad; Bahareh Abbasi

Volume 6, Issue 23 , December 2021, , Pages 5-9

https://doi.org/10.22034/pmj.2021.249035

Abstract
  Background: Lung cancer is the first cause of cancer deaths in the world. Pemetrexed is an antifolate drug used as a first or second-line in the treatment of advanced non-small cell ...  Read More
Effect of ascorbic acid treatment with angiogenesis
Effect of ascorbic acid treatment with angiogenesis

Sareh Bakhshandeh Bavarsad; Amir Mohammadi; Najme Shojaei

Volume 5, Issue 18 , September 2020, , Pages 17-19

https://doi.org/10.22034/pmj.2020.46382

Abstract
  Vitamin C plays is a cofactor for enzymes involved in many processes and has effects that are important for cancer transformation, such as antioxidant defense, transcription, and epigenetic ...  Read More
Original Article
rs78726532 TLR3 gene polymorphism with susceptibility to Hepatitis C virus infection
rs78726532 TLR3 gene polymorphism with susceptibility to Hepatitis C virus infection

Blnd Ibrahim Mohammed; Saeed Megdadi; Vahid Reza Esfahani

Articles in Press, Accepted Manuscript, Available Online from 10 June 2020

https://doi.org/10.22034/pmj.2020.40358

Abstract
  HCV is a blood pathogen that affects approximately 180 million people worldwide. It has the ability to escape its host’s defense mechanism and is considered a resistant species. ...  Read More
Original Article
Effects of iron oxide nanoparticles on MDA-MB-231 breast breast cell line
Effects of iron oxide nanoparticles on MDA-MB-231 breast breast cell line

Ramadhan Ibrahim; Mohammad Ali Saremi; Mohammad Ali Keshavarz Shahbaz; Maryam forouhi

Articles in Press, Corrected Proof, Available Online from 10 June 2020

https://doi.org/10.22034/pmj.2020.40359

Abstract
  Because of their small size, unique physics, and chemical properties, metal nanoparticles can easily cross obstacles and reach their target cells, which makes them an ideal choice for ...  Read More
Original Article
Investigating the relationship between polymorphism rs406193 and the risk of prostate cancer
Investigating the relationship between polymorphism rs406193 and the risk of prostate cancer

Fawziah M. Mohammed; Amir Mohammadi; Najme Shojaei

Articles in Press, Corrected Proof, Available Online from 10 June 2020

https://doi.org/10.22034/pmj.2020.40360

Abstract
  In many cancers, an increase in gene expression of DNMT3b has been reported. This enzyme inhibits the expression of many tumor suppressor genes through the methylation of the promoter ...  Read More
Evaluation of the relationship between intronic polymorphism TPO gene and risk of type 2 diabetes in Tehran population
Evaluation of the relationship between intronic polymorphism TPO gene and risk of type 2 diabetes in Tehran population

Massoud Houshmand; Mehrshad Seresht-Ahmadi; Mahsa Alikarami

Articles in Press, Corrected Proof, Available Online from 10 June 2020

https://doi.org/10.22034/pmj.2020.40361

Abstract
  Obesity and type 2 diabetes are two complex disorders with strong genetic backgrounds, and both disorders cause other diseases and increase mortality. FTO is a protein-coding gene located ...  Read More
Original Article
Investigation of p16 gene promoter methylation in people with cervical cancer and women with papilloma virus infection
Investigation of p16 gene promoter methylation in people with cervical cancer and women with papilloma virus infection

Abdulkarim Karim; Hadi Yari; Ehsan Razeghian; Ali Reza Miri Lavasani

Articles in Press, Corrected Proof, Available Online from 10 June 2020

https://doi.org/10.22034/pmj.2020.40362

Abstract
  Cervical cancer is the second most common cancer and an important cause of death in women worldwide. Objective biomarkers are needed to improve specificity for cervical cancer screening. ...  Read More
Evaluation of miRNA-21 expression in plasma samples of breast cancer patients
Evaluation of miRNA-21 expression in plasma samples of breast cancer patients

kazhaleh Mohammadi; Mehrdad Tavakoli; Nafise Poorhasan; Maryam forouhi

Articles in Press, Corrected Proof, Available Online from 10 June 2020

https://doi.org/10.22034/pmj.2020.40363

Abstract
  According to the World Health Organization, one in eight to ten women will develop breast cancer. Therefore, the development of new blood / serum markers is important as an alternative ...  Read More
Original Article
The effect of vitamin D treatment on the sperm parameters of mice treated with busulfan
The effect of vitamin D treatment on the sperm parameters of mice treated with busulfan

Sahar Hassannejad; Reza Ghamari; Mohammad Ali Saremi; Sadegh Shojaei Baghini

Articles in Press, Corrected Proof, Available Online from 10 June 2020

https://doi.org/10.22034/pmj.2020.40364

Abstract
  Spermatogenesis is a very complex process that can be affected by a number of factors which may lead to reduced fertility or infertility. Busulfan kills spermatogonia stem cells and ...  Read More

Publisher:
AmitisGen TECH Dev Group

Editor-in-Chief:
Prof. Massoud Houshmand

Senior Editor:
Dr.Roya Amirinejad

Editorial Manager:
Dr. Mohammad Ali Saremi

Executive Manager:
Nayyere Moslehi


Frequency: Quarterly

Online ISSN: 2717-3860

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