Personalized Medicine Journal is an open access double-blind peer reviewed publication which is published by AmitisGen Med Tech Group concerned with new concepts and findings in areas related to the personalized medicine issues. PMJ is a quarterly publication, which welcomes original, review, novel and high-impact articles in jornal scope (See journal scope)All submitted manuscripts are checked for similarity through a trustworthy software named iThenticate to be assured about its originality and then rigorously peer-reviewed by the reviewers. The review process of the manuscript normally takes 4-8 weeks. In addition, PMJ awards a prize to the most innovative article of the quarterly. (Read more...)

        

Review Article
Epigenetic as a Novel Biomarker Associated with PAH Exposure and Breast CancerRisk
Epigenetic as a Novel Biomarker Associated with PAH Exposure and Breast CancerRisk

Zainab Adel Abbas; Abbas Raheem Jebur; Abbas Ardalan; Abbas Ghasemzadeh

Volume 7, Issue 25 , June 2022, Pages 1-14

http://dx.doi.org/10.22034/pmj.2022.253549

Abstract
  The pathophysiology and molecular pathways of breast cancer (BC) are still unclear, but it appears that BC is caused by the interaction between genetic susceptibility and environmental ...  Read More
Original Article
Molecular Detection of Fungal APR1 Gene in Serum of Multiple Sclerosis Patients: A Personalized Medicine Research
Molecular Detection of Fungal APR1 Gene in Serum of Multiple Sclerosis Patients: A Personalized Medicine Research

Tohid Piri-Gharaghie; Amineh Zarinnezhad; Bahar Naghian; Romina Babaei

Volume 7, Issue 25 , June 2022, Pages 15-24

http://dx.doi.org/10.22034/pmj.2022.253551

Abstract
  Due to the lack of reliable biomarkers and a thorough understanding of the etiology of multiple sclerosis (MS), the treatment strategy in MS requires a personalized medicine framework ...  Read More
Review Article
The Personalized Medicine Approaches in the Treatment of Corona Virus Disease-2019 (COVID-19): A Review
The Personalized Medicine Approaches in the Treatment of Corona Virus Disease-2019 (COVID-19): A Review

Homeira Zare Chavoshy; Razieh Ghasemi

Volume 7, Issue 25 , June 2022, Pages 25-29

http://dx.doi.org/10.22034/pmj.2022.253552

Abstract
  Personalized medicine is the clinical treatment of diseases that is tailored to the physiologic, molecular genetics and lifestyle characteristics of the patient.Personalized medicine ...  Read More
Original Article
Evaluation of the Effects of Diazinon Toxin on Some Reproductive Parameters in Male Rats
Evaluation of the Effects of Diazinon Toxin on Some Reproductive Parameters in Male Rats

Ghazal Ghajari; Reyhaneh Moosavi

Volume 7, Issue 25 , June 2022, Pages 30-35

http://dx.doi.org/10.22034/pmj.2022.253550

Abstract
  The reproductive system is affected negatively by the organophosphate insecticide diazinon (DZN). Numerous adverse effects on the reproductive system are brought on by it, including ...  Read More
Review Article
Alternatives to Antibiotics GOAL: ELEVATING Antibiotic Resistance During the Post-COVID Period
Alternatives to Antibiotics GOAL: ELEVATING Antibiotic Resistance During the Post-COVID Period

Saber Kabiri-Samani; Mandana Sanatgaran; Nastaran Shojaei-Barjoei; Reyhaneh Moosavi; Parinaz Shaqaqi; Hamidreza Kabiri

Volume 7, Issue 25 , June 2022, Pages 36-42

http://dx.doi.org/10.22034/pmj.2022.253553

Abstract
  The COVID-19 outbreak offers an unmatched chance to take advantage of personalized medicine's benefits for the protection, detection, medication, monitoring, and administration of a ...  Read More
Original Article
TGF-β Isoforms and Receptors: A Gene Expression Analysis in Multiple Sclerosis Patients and Normal Individuals
TGF-β Isoforms and Receptors: A Gene Expression Analysis in Multiple Sclerosis Patients and Normal Individuals

Zeinab Shirvani-Farsani; Mehrdad behmanesh; Mohammad Ali Sahraian

Volume 7, Issue 25 , June 2022, Pages 43-47

http://dx.doi.org/10.22034/pmj.2022.253554

Abstract
  Multiple sclerosis (MS) is a chronic inflammatory disease of the central nervous system (CNS), depicted by lymphocytic infiltration and demyelination. MS is associated with the up-regulation ...  Read More
Comparison of different methods of DNA extraction from paraffin-embedded tissues
Comparison of different methods of DNA extraction from paraffin-embedded tissues

Ramadhan Ibrahim; Saeed Megdadi; Sareh Bakhshandeh bavarsad; Najme Shojaei

Volume 5, Issue 17 , June 2020, , Pages 5-8

http://dx.doi.org/10.22034/pmj.2020.43452

Abstract
  The most common human archival specimens are formalin-fixed and paraffin-embedded tissues. PCR-based techniques have been coupled with new developments in the extraction of DNA from ...  Read More
Increased expression of the lnc H19 gene in the plasma of people with breast cancer
Increased expression of the lnc H19 gene in the plasma of people with breast cancer

kazhaleh Mohammadi; Sadegh Shojaei Baghini; Mohammad Ali Saremi

Volume 5, Issue 17 , June 2020, , Pages 12-14

http://dx.doi.org/10.22034/pmj.2020.43454

Abstract
  The majority of ncRNAs are known as long non-coding RNAs (lncRNAs) whose length exceeds 200 nucleotides. H19, a lncRNA, is the transcription product of the H19 gene, an oncogene in ...  Read More
Analysis of EGFR gene mutations in tissue samples of lung cancer tumors
Analysis of EGFR gene mutations in tissue samples of lung cancer tumors

Blnd Ibrahim Mohammed; Amir Mohammadi; Nafise Poorhasan

Volume 5, Issue 17 , June 2020, , Pages 1-4

http://dx.doi.org/10.22034/pmj.2020.43451

Abstract
  Lung cancer is the leading cause of cancer deaths worldwide. Approximately 25% of nonsmall-cell lung cancers have mutations in the EGFR gene, most of which occur in hotspot regions ...  Read More
Methylenetetrahydrofolate Reductase C677T (rs1801133) Polymorphism and Pemetrexed Treatment Outcome in Patients with Non–Small-Cell Lung Cancer
Methylenetetrahydrofolate Reductase C677T (rs1801133) Polymorphism and Pemetrexed Treatment Outcome in Patients with Non–Small-Cell Lung Cancer

Mohammad Hadi Abbasian; Nafiseh Ansarinejad; Tayeb Ramim; Farshid Fardad; Bahareh Abbasi

Volume 6, Issue 23 , December 2021, , Pages 5-9

http://dx.doi.org/10.22034/pmj.2021.249035

Abstract
  Background: Lung cancer is the first cause of cancer deaths in the world. Pemetrexed is an antifolate drug used as a first or second-line in the treatment of advanced non-small cell ...  Read More
Effect of ascorbic acid treatment with angiogenesis
Effect of ascorbic acid treatment with angiogenesis

Sareh Bakhshandeh Bavarsad; Amir Mohammadi; Najme Shojaei

Volume 5, Issue 18 , September 2020, , Pages 17-19

http://dx.doi.org/10.22034/pmj.2020.46382

Abstract
  Vitamin C plays is a cofactor for enzymes involved in many processes and has effects that are important for cancer transformation, such as antioxidant defense, transcription, and epigenetic ...  Read More
Original Article
rs78726532 TLR3 gene polymorphism with susceptibility to Hepatitis C virus infection
rs78726532 TLR3 gene polymorphism with susceptibility to Hepatitis C virus infection

Blnd Ibrahim Mohammed; Saeed Megdadi; Vahid Reza Esfahani

Articles in Press, Accepted Manuscript, Available Online from 10 June 2020

http://dx.doi.org/10.22034/pmj.2020.40358

Abstract
  HCV is a blood pathogen that affects approximately 180 million people worldwide. It has the ability to escape its host’s defense mechanism and is considered a resistant species. ...  Read More
Original Article
Effects of iron oxide nanoparticles on MDA-MB-231 breast breast cell line
Effects of iron oxide nanoparticles on MDA-MB-231 breast breast cell line

Ramadhan Ibrahim; Mohammad Ali Saremi; Mohammad Ali Keshavarz Shahbaz; Maryam forouhi

Articles in Press, Corrected Proof, Available Online from 10 June 2020

http://dx.doi.org/10.22034/pmj.2020.40359

Abstract
  Because of their small size, unique physics, and chemical properties, metal nanoparticles can easily cross obstacles and reach their target cells, which makes them an ideal choice for ...  Read More
Original Article
Investigating the relationship between polymorphism rs406193 and the risk of prostate cancer
Investigating the relationship between polymorphism rs406193 and the risk of prostate cancer

Fawziah M. Mohammed; Amir Mohammadi; Najme Shojaei

Articles in Press, Corrected Proof, Available Online from 10 June 2020

http://dx.doi.org/10.22034/pmj.2020.40360

Abstract
  In many cancers, an increase in gene expression of DNMT3b has been reported. This enzyme inhibits the expression of many tumor suppressor genes through the methylation of the promoter ...  Read More
Evaluation of the relationship between intronic polymorphism TPO gene and risk of type 2 diabetes in Tehran population
Evaluation of the relationship between intronic polymorphism TPO gene and risk of type 2 diabetes in Tehran population

Massoud Houshmand; Mehrshad Seresht-Ahmadi; Mahsa Alikarami

Articles in Press, Corrected Proof, Available Online from 10 June 2020

http://dx.doi.org/10.22034/pmj.2020.40361

Abstract
  Obesity and type 2 diabetes are two complex disorders with strong genetic backgrounds, and both disorders cause other diseases and increase mortality. FTO is a protein-coding gene located ...  Read More
Original Article
Investigation of p16 gene promoter methylation in people with cervical cancer and women with papilloma virus infection
Investigation of p16 gene promoter methylation in people with cervical cancer and women with papilloma virus infection

Abdulkarim Karim; Hadi Yari; Ehsan Razeghian; Ali Reza Miri Lavasani

Articles in Press, Corrected Proof, Available Online from 10 June 2020

http://dx.doi.org/10.22034/pmj.2020.40362

Abstract
  Cervical cancer is the second most common cancer and an important cause of death in women worldwide. Objective biomarkers are needed to improve specificity for cervical cancer screening. ...  Read More
Evaluation of miRNA-21 expression in plasma samples of breast cancer patients
Evaluation of miRNA-21 expression in plasma samples of breast cancer patients

kazhaleh Mohammadi; Mehrdad Tavakoli; Nafise Poorhasan; Maryam forouhi

Articles in Press, Corrected Proof, Available Online from 10 June 2020

http://dx.doi.org/10.22034/pmj.2020.40363

Abstract
  According to the World Health Organization, one in eight to ten women will develop breast cancer. Therefore, the development of new blood / serum markers is important as an alternative ...  Read More
Original Article
The effect of vitamin D treatment on the sperm parameters of mice treated with busulfan
The effect of vitamin D treatment on the sperm parameters of mice treated with busulfan

Sahar Hassannejad; Reza Ghamari; Mohammad Ali Saremi; Sadegh Shojaei Baghini

Articles in Press, Corrected Proof, Available Online from 10 June 2020

http://dx.doi.org/10.22034/pmj.2020.40364

Abstract
  Spermatogenesis is a very complex process that can be affected by a number of factors which may lead to reduced fertility or infertility. Busulfan kills spermatogonia stem cells and ...  Read More

Publisher:
AmitisGen Med Tech Group

Editor-in-Chief:
Prof. Massoud Houshmand

Senior Editor:
Dr. Roya Amirinejad

Editorial Manager:
Dr. Mohammad Ali Saremi

Executive Manager:
Nayyere Moslehi


Frequency: Quarterly

Online ISSN: 2717-3860

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