Personalized Medicine Journal

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Volume 7 (2022)
Volume 6 (2021)
Volume 5 (2020)
Volume 4 (2019)
Volume 3 (2018)
Volume 2 (2017)
Volume 1 (2016)

Personalized Medicine Journal is an open access double-blind peer reviewed publication which is published by AmitisGen TECH Dev Group concerned with new concepts and findings in areas related to the personalized medicine issues. PMJ is a quarterly publication, which welcomes original, review, novel and high-impact articles in jornal scope (See journal scope). All submitted manuscripts are checked for similarity through a trustworthy software named iThenticate to be assured about its originality and then rigorously peer-reviewed by the reviewers. The review process of the manuscript normally takes 4-8 weeks. In addition, PMJ awards a prize to the most innovative article of the quarterly. (Read more...)

        

Case Study
Metastatic Malignancy Presenting as Thrombotic Thrombocytopenia Purpura; Report of Two Cases
Metastatic Malignancy Presenting as Thrombotic Thrombocytopenia Purpura; Report of Two Cases

Hamid Rezvani; Mehdi Tabarraee; Mojtaba Ghadyani; Seyed Amir Sheikholeslami; Hamideh Rahmani; Soude Ramezan Nejad; Aida Iranpour

Volume 8, Issue 28 , March 2023, Pages 1-4

https://doi.org/10.22034/pmj.2023.702079

Abstract
  BackgroundCancer associated thrombotic microangiopathy (CA-TMA) is a rare diagnosis that while confronting a patient with evidence of microangiopathic hemolytic anemia and thrombocytopenia ...  Read More
Review Article
Mechanistic and Diagnostic Roles of Kallikrein Related Peptidases 2 (KLK2) in Prostate Cancer
Mechanistic and Diagnostic Roles of Kallikrein Related Peptidases 2 (KLK2) in Prostate Cancer

Ghazaleh Khosroabadi; Saghar Yousefnia

Volume 8, Issue 28 , March 2023, Pages 5-12

https://doi.org/10.22034/pmj.2023.702080

Abstract
  Kallikrein related peptidases (KLKs) are a group of serine-like proteases such as chemo trypsin and trypsin, which are regulated by steroid hormones and play a vital role in a variety ...  Read More
Review Article
Relationship between LncRNAs and Multiple Sclerosis (MS)
Relationship between LncRNAs and Multiple Sclerosis (MS)

Reyhaneh Tahouri; Ghasem Ghorbani Valezaghard

Volume 8, Issue 28 , March 2023, Pages 13-19

https://doi.org/10.22034/pmj.2023.702081

Abstract
  Multiple sclerosis (MS), the most common inflammatory demyelinating illness of the central nervous system (CNS), presents a range of clinical symptoms. The body’s immune system ...  Read More
Original Article
Vitamin D Binding Protein Gene Polymorphisms and its Association with Type 2 Diabetes Mellitus in an Iranian Population
Vitamin D Binding Protein Gene Polymorphisms and its Association with Type 2 Diabetes Mellitus in an Iranian Population

Heidar Aziznejad; Ares Alizadeh; Marva Aziznejad; Zahra Sanjideh; Parisa Maziri

Volume 8, Issue 28 , March 2023, Pages 20-25

https://doi.org/10.22034/pmj.2023.702082

Abstract
  Polymorphisms of Vitamin D-binding protein (DBP) may represent a risk factor for susceptibility to Type 2 Diabetes Mellitus (T2DM). Two polymorphisms are common at codons 420 (ACG to ...  Read More
Review Article
Personalized Medicine Approach and the Application of iPSCs in Neurological Diseases
Personalized Medicine Approach and the Application of iPSCs in Neurological Diseases

Jafar Jafari

Volume 8, Issue 28 , March 2023, Pages 26-34

https://doi.org/10.22034/pmj.2023.702083

Abstract
  A number of animal disease models have been created in the past to investigate the molecular basis of neurological diseases and identify novel treatments, but their effectiveness has ...  Read More
Review Article
Treatment of Rheumatoid Arthritis Based on Personalized Medicine: a New Approach in Rheumatology
Treatment of Rheumatoid Arthritis Based on Personalized Medicine: a New Approach in Rheumatology

Hossein Amin-Anaraki; Saber Kabiri-Samani

Volume 8, Issue 28 , March 2023, Pages 35-45

https://doi.org/10.22034/pmj.2023.702084

Abstract
  In the twenty-first century, there still needs more clarity on rheumatoid arthritis (RA). Rheumatoid arthritis is a widespread but heterogeneous illness with a broad range in its history, ...  Read More
Comparison of different methods of DNA extraction from paraffin-embedded tissues
Comparison of different methods of DNA extraction from paraffin-embedded tissues

Ramadhan Ibrahim; Saeed Megdadi; Sareh Bakhshandeh bavarsad; Najme Shojaei

Volume 5, Issue 17 , June 2020, , Pages 5-8

https://doi.org/10.22034/pmj.2020.43452

Abstract
  The most common human archival specimens are formalin-fixed and paraffin-embedded tissues. PCR-based techniques have been coupled with new developments in the extraction of DNA from ...  Read More
Increased expression of the lnc H19 gene in the plasma of people with breast cancer
Increased expression of the lnc H19 gene in the plasma of people with breast cancer

kazhaleh Mohammadi; Sadegh Shojaei Baghini; Mohammad Ali Saremi

Volume 5, Issue 17 , June 2020, , Pages 12-14

https://doi.org/10.22034/pmj.2020.43454

Abstract
  The majority of ncRNAs are known as long non-coding RNAs (lncRNAs) whose length exceeds 200 nucleotides. H19, a lncRNA, is the transcription product of the H19 gene, an oncogene in ...  Read More
Polycystic ovary syndrome and genetic factors influencing its development: A review article
Polycystic ovary syndrome and genetic factors influencing its development: A review article

Tohid Piri-Gharaghie

Volume 6, Issue 23 , December 2021, , Pages 25-29

https://doi.org/10.22034/pmj.2021.249631

Abstract
  Polycystic ovary syndrome (PCOS) is a common infertility disorder, affecting a significant proportion of the global population. This syndrome has been one of the most controversial ...  Read More
Analysis of EGFR gene mutations in tissue samples of lung cancer tumors
Analysis of EGFR gene mutations in tissue samples of lung cancer tumors

Blnd Ibrahim Mohammed; Amir Mohammadi; Nafise Poorhasan

Volume 5, Issue 17 , June 2020, , Pages 1-4

https://doi.org/10.22034/pmj.2020.43451

Abstract
  Lung cancer is the leading cause of cancer deaths worldwide. Approximately 25% of nonsmall-cell lung cancers have mutations in the EGFR gene, most of which occur in hotspot regions ...  Read More
Methylenetetrahydrofolate Reductase C677T (rs1801133) Polymorphism and Pemetrexed Treatment Outcome in Patients with Non–Small-Cell Lung Cancer
Methylenetetrahydrofolate Reductase C677T (rs1801133) Polymorphism and Pemetrexed Treatment Outcome in Patients with Non–Small-Cell Lung Cancer

Mohammad Hadi Abbasian; Nafiseh Ansarinejad; Tayeb Ramim; Farshid Fardad; Bahareh Abbasi

Volume 6, Issue 23 , December 2021, , Pages 5-9

https://doi.org/10.22034/pmj.2021.249035

Abstract
  Background: Lung cancer is the first cause of cancer deaths in the world. Pemetrexed is an antifolate drug used as a first or second-line in the treatment of advanced non-small cell ...  Read More
Original Article
rs78726532 TLR3 gene polymorphism with susceptibility to Hepatitis C virus infection
rs78726532 TLR3 gene polymorphism with susceptibility to Hepatitis C virus infection

Blnd Ibrahim Mohammed; Saeed Megdadi; Vahid Reza Esfahani

Articles in Press, Accepted Manuscript, Available Online from 10 June 2020

https://doi.org/10.22034/pmj.2020.40358

Abstract
  HCV is a blood pathogen that affects approximately 180 million people worldwide. It has the ability to escape its host’s defense mechanism and is considered a resistant species. ...  Read More
Original Article
Effects of iron oxide nanoparticles on MDA-MB-231 breast breast cell line
Effects of iron oxide nanoparticles on MDA-MB-231 breast breast cell line

Ramadhan Ibrahim; Mohammad Ali Saremi; Mohammad Ali Keshavarz Shahbaz; Maryam forouhi

Articles in Press, Corrected Proof, Available Online from 10 June 2020

https://doi.org/10.22034/pmj.2020.40359

Abstract
  Because of their small size, unique physics, and chemical properties, metal nanoparticles can easily cross obstacles and reach their target cells, which makes them an ideal choice for ...  Read More
Original Article
Investigating the relationship between polymorphism rs406193 and the risk of prostate cancer
Investigating the relationship between polymorphism rs406193 and the risk of prostate cancer

Fawziah M. Mohammed; Amir Mohammadi; Najme Shojaei

Articles in Press, Corrected Proof, Available Online from 10 June 2020

https://doi.org/10.22034/pmj.2020.40360

Abstract
  In many cancers, an increase in gene expression of DNMT3b has been reported. This enzyme inhibits the expression of many tumor suppressor genes through the methylation of the promoter ...  Read More
Evaluation of the relationship between intronic polymorphism TPO gene and risk of type 2 diabetes in Tehran population
Evaluation of the relationship between intronic polymorphism TPO gene and risk of type 2 diabetes in Tehran population

Massoud Houshmand; Mehrshad Seresht-Ahmadi; Mahsa Alikarami

Articles in Press, Corrected Proof, Available Online from 10 June 2020

https://doi.org/10.22034/pmj.2020.40361

Abstract
  Obesity and type 2 diabetes are two complex disorders with strong genetic backgrounds, and both disorders cause other diseases and increase mortality. FTO is a protein-coding gene located ...  Read More
Original Article
Investigation of p16 gene promoter methylation in people with cervical cancer and women with papilloma virus infection
Investigation of p16 gene promoter methylation in people with cervical cancer and women with papilloma virus infection

Abdulkarim Karim; Hadi Yari; Ehsan Razeghian; Ali Reza Miri Lavasani

Articles in Press, Corrected Proof, Available Online from 10 June 2020

https://doi.org/10.22034/pmj.2020.40362

Abstract
  Cervical cancer is the second most common cancer and an important cause of death in women worldwide. Objective biomarkers are needed to improve specificity for cervical cancer screening. ...  Read More
Evaluation of miRNA-21 expression in plasma samples of breast cancer patients
Evaluation of miRNA-21 expression in plasma samples of breast cancer patients

kazhaleh Mohammadi; Mehrdad Tavakoli; Nafise Poorhasan; Maryam forouhi

Articles in Press, Corrected Proof, Available Online from 10 June 2020

https://doi.org/10.22034/pmj.2020.40363

Abstract
  According to the World Health Organization, one in eight to ten women will develop breast cancer. Therefore, the development of new blood / serum markers is important as an alternative ...  Read More
Original Article
The effect of vitamin D treatment on the sperm parameters of mice treated with busulfan
The effect of vitamin D treatment on the sperm parameters of mice treated with busulfan

Sahar Hassannejad; Reza Ghamari; Mohammad Ali Saremi; Sadegh Shojaei Baghini

Articles in Press, Corrected Proof, Available Online from 10 June 2020

https://doi.org/10.22034/pmj.2020.40364

Abstract
  Spermatogenesis is a very complex process that can be affected by a number of factors which may lead to reduced fertility or infertility. Busulfan kills spermatogonia stem cells and ...  Read More
Personalized Medicine Journal

Publisher:
AmitisGen TECH Dev Group

Editor-in-Chief:
Prof. Massoud Houshmand

Senior Editor:
Dr.Roya Amirinejad

Editorial Manager:
Dr. Mohammad Ali Saremi

Executive Manager:
Nayyere Moslehi

Frequency: Quarterly

Online ISSN: 2717-3860

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