Personalized Medicine Journal is an open access Publication, accepting articles in Persian since 2016 until 2019. Afterwards, to share our knowledge worldwide, PMJ has started publishing English articles. PMJ welcomes original, review, novel and high-impact articles related to the personalized medicine issues. PMJ has been indexed in databases; Google scholar, Magiran, and CIVILICA

All submitted manuscripts are checked for similarity through a trustworthy software named iThenticate to be assured about its originality and then rigorously peer-reviewed by the reviewers. The review process of the manuscript normally takes 4-8 weeks. In addition, PMJ awards a prize to the most innovative article of the quarterly.

Original Article
Association between rs362746 polymorphism of RELN and Schizophrenia in Iranian Patients
1. Association between rs362746 polymorphism of RELN and Schizophrenia in Iranian Patients

Shima Alimohammadi

Volume 6, Issue 21 , Spring 2021, Pages 1-3

http://dx.doi.org/10.22034/pmj.2021.244727

Abstract
  Genetic studies, there is a potential association of RELN with some psychologicaldisorders such as Autism Spectrum Disorders (ASD) schizophrenia (SCZ). The RELNgene is located on chromosome ...  Read More
Original Article
A relationship between two polymorphisms (rs2660 and rs1800450) and coronavirus (COVID-19) in Iranian population
2. A relationship between two polymorphisms (rs2660 and rs1800450) and coronavirus (COVID-19) in Iranian population

Zahra Sadeghi; Hossein Pakzad; Massoud Houshmand

Volume 6, Issue 21 , Spring 2021, Pages 4-6

http://dx.doi.org/10.22034/pmj.2021.244728

Abstract
  Warning of the World Health Organization (WHO) indicates that novel coronavirus (COVID-19) is pandemic and causes global concern. COVID-19 has acute respiratory symptoms which ...  Read More
Review Article
Investigating the causes of antibiotic resistance in bacteria
3. Investigating the causes of antibiotic resistance in bacteria

AmirHossein Akbari Aghababa; Mona Nadi

Volume 6, Issue 21 , Spring 2021, Pages 7-11

http://dx.doi.org/10.22034/pmj.2021.244729

Abstract
  The discovery and production of (synthetic) antibiotics in the first half of the previous century has been one of medicine’s greatest achievements. The use of antimicrobial agents ...  Read More
Review Article
Epithelial-mesenchymal transition in breast cancer
4. Epithelial-mesenchymal transition in breast cancer

Mohammad Ali Saremi; Nafise Poorhasan

Volume 6, Issue 21 , Spring 2021, Pages 12-16

http://dx.doi.org/10.22034/pmj.2021.244731

Abstract
  One of the key molecular mechanisms contributing to the metastatic progression is epithelial to mesenchymal transition (EMT), which drives invasion and migration of various cancer including ...  Read More
Review Article
Covid19 disease and the effect of genetic factors on its severity and weakness
5. Covid19 disease and the effect of genetic factors on its severity and weakness

Abbas Ghasemzadeh; Vahidreza Esfahani

Volume 6, Issue 21 , Spring 2021, Pages 17-22

http://dx.doi.org/10.22034/pmj.2021.244730

Abstract
  Severe Acute Respiratory SyndromeCoronavirus 2 (SARS-CoV-2), is a severe infection with respiratory and systemicmanifestations. This infectious disease has a complex course and manifests ...  Read More
Review Article
The application of DNA-conjugated gold nanoparticles to detect metabolites and nucleic acids in personalized medicine
6. The application of DNA-conjugated gold nanoparticles to detect metabolites and nucleic acids in personalized medicine

Roya Amirinejad; Zeinab Shirvani-Farsani; Sohameh Mohebbi

Volume 6, Issue 21 , Spring 2021, Pages 23-25

http://dx.doi.org/10.22034/pmj.2021.244733

Abstract
  In this article, the features of DNA-functionalized goldnanoparticles (GNRs), including the size-dependent color, the amount of conjugated DNA, and the fluorescence quenchers will be ...  Read More
Comparison of different methods of DNA extraction from paraffin-embedded tissues
1. Comparison of different methods of DNA extraction from paraffin-embedded tissues

Ramadhan Ibrahim; Saeed Megdadi; Sareh Bakhshandeh bavarsad; Najme Shojaei

Volume 5, Issue 17 , Spring 2020, , Pages 5-8

http://dx.doi.org/10.22034/pmj.2020.43452

Abstract
  The most common human archival specimens are formalin-fixed and paraffin-embedded tissues. PCR-based techniques have been coupled with new developments in the extraction of DNA from ...  Read More
Analysis of EGFR gene mutations in tissue samples of lung cancer tumors
2. Analysis of EGFR gene mutations in tissue samples of lung cancer tumors

Blnd Ibrahim Mohammed; Amir Mohammadi; Nafise Poorhasan

Volume 5, Issue 17 , Spring 2020, , Pages 1-4

http://dx.doi.org/10.22034/pmj.2020.43451

Abstract
  Lung cancer is the leading cause of cancer deaths worldwide. Approximately 25% of nonsmall-cell lung cancers have mutations in the EGFR gene, most of which occur in hotspot regions ...  Read More
Increased expression of the lnc H19 gene in the plasma of people with breast cancer
3. Increased expression of the lnc H19 gene in the plasma of people with breast cancer

kazhaleh Mohammadi; Sadegh Shojaei Baghini; Mohammad Ali Saremi

Volume 5, Issue 17 , Spring 2020, , Pages 12-14

http://dx.doi.org/10.22034/pmj.2020.43454

Abstract
  The majority of ncRNAs are known as long non-coding RNAs (lncRNAs) whose length exceeds 200 nucleotides. H19, a lncRNA, is the transcription product of the H19 gene, an oncogene in ...  Read More
Effect of ascorbic acid treatment with angiogenesis
4. Effect of ascorbic acid treatment with angiogenesis

Sareh Bakhshandeh Bavarsad; Amir Mohammadi; Najme Shojaei

Volume 5, Issue 18 , Summer 2020, , Pages 17-19

http://dx.doi.org/10.22034/pmj.2020.46382

Abstract
  Vitamin C plays is a cofactor for enzymes involved in many processes and has effects that are important for cancer transformation, such as antioxidant defense, transcription, and epigenetic ...  Read More
The application of DNA-conjugated gold nanoparticles to detect metabolites and nucleic acids in personalized medicine
5. The application of DNA-conjugated gold nanoparticles to detect metabolites and nucleic acids in personalized medicine

Roya Amirinejad; Zeinab Shirvani-Farsani; Sohameh Mohebbi

Volume 6, Issue 21 , Spring 2021, , Pages 23-25

http://dx.doi.org/10.22034/pmj.2021.244733

Abstract
  In this article, the features of DNA-functionalized goldnanoparticles (GNRs), including the size-dependent color, the amount of conjugated DNA, and the fluorescence quenchers will be ...  Read More
Original Article
rs78726532 TLR3 gene polymorphism with susceptibility to Hepatitis C virus infection
1. rs78726532 TLR3 gene polymorphism with susceptibility to Hepatitis C virus infection

Blnd Ibrahim Mohammed; Saeed Megdadi; Vahid Reza Esfahani

Articles in Press, Accepted Manuscript, Available Online from 10 June 2020

http://dx.doi.org/10.22034/pmj.2020.40358

Abstract
  HCV is a blood pathogen that affects approximately 180 million people worldwide. It has the ability to escape its host’s defense mechanism and is considered a resistant species. ...  Read More
Original Article
Effects of iron oxide nanoparticles on MDA-MB-231 breast breast cell line
2. Effects of iron oxide nanoparticles on MDA-MB-231 breast breast cell line

Ramadhan Ibrahim; Mohammad Ali Saremi; Mohammad Ali Keshavarz Shahbaz; Maryam forouhi

Articles in Press, Corrected Proof, Available Online from 10 June 2020

http://dx.doi.org/10.22034/pmj.2020.40359

Abstract
  Because of their small size, unique physics, and chemical properties, metal nanoparticles can easily cross obstacles and reach their target cells, which makes them an ideal choice for ...  Read More
Original Article
Investigating the relationship between polymorphism rs406193 and the risk of prostate cancer
3. Investigating the relationship between polymorphism rs406193 and the risk of prostate cancer

Fawziah M. Mohammed; Amir Mohammadi; Najme Shojaei

Articles in Press, Corrected Proof, Available Online from 10 June 2020

http://dx.doi.org/10.22034/pmj.2020.40360

Abstract
  In many cancers, an increase in gene expression of DNMT3b has been reported. This enzyme inhibits the expression of many tumor suppressor genes through the methylation of the promoter ...  Read More
Evaluation of the relationship between intronic polymorphism TPO gene and risk of type 2 diabetes in Tehran population
4. Evaluation of the relationship between intronic polymorphism TPO gene and risk of type 2 diabetes in Tehran population

Massoud Houshmand; Mehrshad Seresht-Ahmadi; Mahsa Alikarami

Articles in Press, Corrected Proof, Available Online from 10 June 2020

http://dx.doi.org/10.22034/pmj.2020.40361

Abstract
  Obesity and type 2 diabetes are two complex disorders with strong genetic backgrounds, and both disorders cause other diseases and increase mortality. FTO is a protein-coding gene located ...  Read More
Original Article
Investigation of p16 gene promoter methylation in people with cervical cancer and women with papilloma virus infection
5. Investigation of p16 gene promoter methylation in people with cervical cancer and women with papilloma virus infection

Abdulkarim Karim; Hadi Yari; Ehsan Razeghian; Ali Reza Miri Lavasani

Articles in Press, Corrected Proof, Available Online from 10 June 2020

http://dx.doi.org/10.22034/pmj.2020.40362

Abstract
  Cervical cancer is the second most common cancer and an important cause of death in women worldwide. Objective biomarkers are needed to improve specificity for cervical cancer screening. ...  Read More
Evaluation of miRNA-21 expression in plasma samples of breast cancer patients
6. Evaluation of miRNA-21 expression in plasma samples of breast cancer patients

kazhaleh Mohammadi; Mehrdad Tavakoli; Nafise Poorhasan; Maryam forouhi

Articles in Press, Corrected Proof, Available Online from 10 June 2020

http://dx.doi.org/10.22034/pmj.2020.40363

Abstract
  According to the World Health Organization, one in eight to ten women will develop breast cancer. Therefore, the development of new blood / serum markers is important as an alternative ...  Read More
Original Article
The effect of vitamin D treatment on the sperm parameters of mice treated with busulfan
7. The effect of vitamin D treatment on the sperm parameters of mice treated with busulfan

Sahar Hassannejad; Reza Ghamari; Mohammad Ali Saremi; Sadegh Shojaei Baghini

Articles in Press, Corrected Proof, Available Online from 10 June 2020

http://dx.doi.org/10.22034/pmj.2020.40364

Abstract
  Spermatogenesis is a very complex process that can be affected by a number of factors which may lead to reduced fertility or infertility. Busulfan kills spermatogonia stem cells and ...  Read More

Publisher:
AmitisGen Med Tech Group

Editor-in-Chief:
  Prof. Massoud Houshmand

Senior Editor:
  Dr. Roya Amirinejad

Managing Editor:
  Dr. Mohammad Ali Saremi

Executive Manager:
  Nayyere Moslehi


Online ISSN: 2717-3860

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