Document Type : Review Article


1 Department of Biotechnology, Faculty of Biological Sciences, Islamic Azad University of East Tehran, Tehran, Iran

2 Department of Biology, Faculty of Basic Sciences, Islamic Azad University of North Tehran, Tehran, Iran.

3 Faculty of Pharmacy, Tehran University of Medical Sciences, Tehran, Iran.

4 Department of Biology, Faculty of Basic Sciences, Islamic Azad University of East Tehran, Tehran, Iran

5 Reference health laboratory, Ministry of health and medical education


The current study identified pathogenic variables associated with increased mortality risk in infectious diseases using predictive analysis and a combination of genotypic, phenotypic, and medical data. The quick nucleic acid-based clinical assessment might affect the spread of hospital-acquired illnesses, and we think that such life-saving operations should be carried out closer to the individual, preferably in 24/7 medical facilities' specialized labs. Personalized medicine notions are relevant in infections for the (rapid) characterization of a disease-causing microbial community and perseverance of its antibiotic susceptibility characteristic to guide a suitable antibiotic therapy for the proper care of the individual. Personalized medicine aims to interrogate a patient's genetic data, and pharmacodynamics polymorphisms, and guide drug options and dosage. This work demonstrates the potential use of fundamental genetic analysis in treating infectious diseases and theoretically justifies the value of customized therapy


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