Document Type : Review Article

Authors

• Homeira Zare Chavoshy
• Fereshteh Barati
• Razieh Ghasemi

Department of Nanotechnology, Jabir Ibn Hayyan Institute, Technical and Vocational Training Organization, Isfahan, Iran

Abstract

Alzheimer's disease (AD) is a neurodegenerative disease that leads to progressive and incurable cognitive and behavioral disorders. Personalized medicine, which is also called precision medicine, represents an approach to the treatment of the disease with the aim of improving the effectiveness of the treatment, which stops or slows the disease in an optimal and targeted manner based on a certain time. It enables physician to accurately and efficiently identify the most effective treatment. Personalized medicine is based on molecular knowledge. Genome sequencing by the Human Genome Project (HGP) represents one of the most powerful tools for personalized medicine, as well as transcriptomics, proteomics and metabolomics development which can be used for both disease prediction and better treatment. In this paper, we will review the strategies that personalized medicine offers for the treatment of AD for the future.

Keywords

• Personalized medicine
• Alzheimer's disease
• β-amyloid peptide
• Dementia