Personalized and Precision Medicine Journal
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Evaluation of Severity Persistent Asthma with Hemophilus Influenza Infection in Asthmatic Patients

Document Type : Original Article

Authors

Emal Zoweiar Alsheihani 1
Ali Neamati 2
Mohammad Reza Khakzad 3

1 MSc of Cellular & Molecular Biology, Department of Biology, Mashhad Branch, Islamic Azad University, Mashhad, Iran

2 Associate Professor of Physiology, Department of Biology, Mashhad Branch, Islamic Azad University, Mashhad Iran

3 Assistant of Immunology, Innovative Medical Research Center, Department of Immunology, Mashhad Branch, Islamic Azad University, Mashhad, Iran

https://doi.org/10.22034/pmj.2024.713768
Abstract
Asthma is one of the most common non-communicable diseases characterized by reversible obstruction of airflow. It poses many problems for all age groups from infancy to old age. Various studies have shown that the occurrence of viral infections is associated with the severity of asthma symptoms so it can be prevented by controlling viral agents. In this study, the severity of the symptoms of persistent severe asthma with Haemophilus influenza infection was investigated. 31 patients with asthma with different degrees of disease were studied in this study. The results showed that in patients with asthma, the percentage of people with Haemophilus influenza was 71% and in 29% of other asthma cases, Haemophilus influenza virus was not observed. The relationship between asthma, cough and dyspnea with Haemophilus influenza infection showed that with increasing asthma symptoms, the severity of infection increases, and no significant association was observed between cough and dyspnea with Haemophilus influenza. Therefore, the results of this study clearly show that Haemophilus influenzae virus causes asthma symptoms to worsen in patients.

Keywords

Asthma
Haemophilus influenza
Real-time PCR
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Personalized and Precision Medicine Journal
Volume 9, Issue 33 - Serial Number 33
Original article
Spring 2024
Pages 47-54

  • Receive Date 24 February 2024
  • Revise Date 17 April 2024
  • Accept Date 20 May 2024

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