Personalized and Precision Medicine Journal
Where Innovations Meets Personalized and Precision Medicine

Aptamer-Based Approaches in Oncology

Document Type : Review Article

Authors

Behnoush Khashei 1
Parisa Haghpour 2

1 Department of pathobiology, faculty of veterinary science, Bu Ali Sina university, Hamedan, Iran

2 Department of Biotechnology, Alzahra Universit, Tehran, Iran

https://doi.org/10.22034/pmj.2024.715089
Abstract
Cancer is a significant global cause of mortality, and enhancing therapy is essential to save lives and minimise adverse consequences. Aptamers, composed of DNA or RNA, have the potential for cancer treatment by precise targeting of certain molecules. Aptamers, unlike conventional therapies such as chemotherapy, have the specific objective of delivering medications directly to cancer cells, while reducing injury to healthy cells. This paper examines the process of aptamer development and utilisation in cancer treatment, with a specific emphasis on their capacity to enhance therapy and surmount drug resistance. Additionally, it explores the obstacles and potential advancements in using aptamers to transform cancer therapy.

Keywords

Aptamer
Cancer
Therapy
SELEX
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Personalized and Precision Medicine Journal
Volume 9, Issue 34
Original article
Summer 2024
Pages 9-13

  • Receive Date 20 April 2024
  • Revise Date 15 July 2024
  • Accept Date 16 August 2024

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