Personalized and Precision Medicine Journal
Where Innovations Meets Personalized and Precision Medicine

The Impact of Anesthesia on Cancer Outcomes

Document Type : Review Article

Authors

Mahtab Dolatabadi 1
Yasaman Vojgani 2

1 Kamali Hospital, Alborz University of Medical Science, Anesthesiology Department, Tehran, Iran

2 Department of Molecular Medicine, Faculty of Advanced Technologies in Medicine, Iran University of Medical Sciences, Tehran, Iran

https://doi.org/10.22034/pmj.2024.715090
Abstract
In cancer treatment, anesthesia is commonly used during surgery to remove tumors, as well as for other procedures like biopsies, radiation therapy, and chemotherapy administration. Some research suggests that the choice of specific anesthetic drugs and nerve-sparing techniques can have a significant impact on cancer recurrence rates and overall patient survival. It is well-established that a patient's immune system plays a direct role in postoperative complications and long-term outcomes, highlighting the importance of optimizing anesthesia to minimize potential immune system suppression and improve immune function during cancer surgery. Recent studies have revealed a strong connection between the type of anesthesia used during surgery and the likelihood of cancer relapse and related mortality. Therefore, it is crucial to select the appropriate anesthesia technique for cancer resection, focusing on reversible effects, rapid recovery, and resistance to feedback. The specific anesthetic agents used during surgery have a significant impact on survival rates and the risk of cancer-related mortality. Genetic influences on anesthesia response are significant for improving patient care and achieving better results. Additionally, personalized medicine, which combines diagnostic testing and treatment, is now a clinical reality. Anesthesia's effects on depth, pain signals, vital signs, and the motor system are complex and not fully understood, and many researchers believe that anesthesia is regulated by multiple genes, although further research is needed to identify them and understand how they are regulated. The relationship between anesthesia and cancer is complex and evolving with implications for medical treatment. Limited evidence suggests that anesthesia and surgery-related factors can affect cancer biology and outcomes. Further research is needed to understand these interactions and develop strategies for improving cancer care during surgery. Better understanding can lead to safer and more effective cancer treatment, benefitting patients.

Keywords

Anesthesia
Cancer
Radiation therapy
Chemotherapy
Personalized Medicine
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Personalized and Precision Medicine Journal
Volume 9, Issue 34
Original article
Summer 2024
Pages 14-19

  • Receive Date 03 May 2024
  • Revise Date 17 July 2024
  • Accept Date 27 August 2024

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