Where Innovations Meets Personalized and Precision Medicine

Pharmacogenomics: Unlocking the Future of Personalized Medicine and Precision Drug Development

Document Type : Review Article

Author

Assistant doctor, Neurology Department, 93413 Cham, Germany.

Abstract
Pharmacogenomics is a relatively new subject that utilizes genomics and pharmacology to investigate the ways in which genetic variants influence individual responses to treatment with pharmaceuticals. A departure from the conventional "one-size-fits-all" treatment strategy is marked by the advent of pharmacogenomics, which makes it possible to tailor pharmacological regimens to the specific genetic profile of an individual. Significant improvements in pharmacological efficacy, reductions in adverse drug reactions (ADRs), and assistance in the development of drugs that are both safe and effective for a wide range of conditions are all possible outcomes of this domain. The purpose of this study is to investigate the prospective results of pharmacogenomics, with a particular emphasis on the function it plays in the process of drug development and its incorporation into personalized medicine. The purpose of this study is to investigate the genetic characteristics that influence the metabolism, efficacy, and toxicity of drugs, as well as to investigate the regulatory framework that is associated with pharmacogenomics testing. This paper provides a synopsis of the most important genes that are involved in pharmacogenomic responses, as well as a discussion of the potential difficulties that may arise in their practical use and the anticipated breakthroughs in this area of study.

Keywords

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Volume 10, Issue 37 - Serial Number 37
Original article
Spring 2025
Pages 39-47

  • Receive Date 22 January 2025
  • Revise Date 13 April 2024
  • Accept Date 18 May 2025